小剂量X线全身照射对小鼠免疫功能的影响  

The influence of low dose X-ray whole bodyirradiation on mouse immunofunctions

作　　者：魏道严[1] 黄帼[1] 汪思应[2] 金敖兴[3] 

机构地区：[1]安徽医科大学核医学教研室,230032 [2]安徽医科大学肿瘤研究室,230032 [3]安徽医科大学,230032

出　　处：《安徽医科大学学报》1996年第5期393-395,共3页Acta Universitatis Medicinalis Anhui

摘　　要：就75mGyX线全身照射对小鼠免疫功能的影响进行了研究.结果发现,与未照射的对照组相比,照射后24h小鼠脾及胸腺有核细胞数明显增加(P<0.05),巨噬细胞功能增强(P<0.01),脾细胞NK细胞毒活性及其对ConA的反应性明显提高(P<0.01).上述结果提示,小剂量X线全身照射可对机体的免疫机能产生刺激作用.The influence of 75 mGy X -ray whole body irradiation on immunofunctions inmice was investigated in this paper. The results demonstrated that, as compared with those of unirradiated control mice, the nucleate cells in spleens and thymus increased obviously (P <0. 05),the function of macrophage enhanced greatly (P<0. 01),and splenocyte's NK cyto-toxity and its responsibility to ConA increaded significantly (P<0. 01)in the irradiated mice. Our results suggest that low dose X-ray whole body irradiation has the augmentative effect on immnofunctions.

关 键 词：辐射剂量 全身照射 免疫功能 X线 

分 类 号：R144.1[医药卫生—公共卫生与预防医学]