降糖通脉颗粒对家兔四氧嘧啶糖尿病的效果观察  

Effects of Jiangtangtongmai Granule on Alloxan-induced Diabetes of Rabbits

作　　者：翦林宏[1] 杨莹[1] 首弟武[1] 

机构地区：[1]湖南省中医药研究院中药研究所,长沙410013

出　　处：《中国比较医学杂志》2006年第11期661-663,共3页Chinese Journal of Comparative Medicine

摘　　要：目的观察降糖通脉颗粒对家兔四氧嘧啶糖尿病的效果。方法通过建立家兔四氧嘧啶糖尿病模型,研究降糖通脉颗粒对动物血糖、胰岛素、胰高血糖素、超氧化物歧化酶(SOD)和丙二醛(MDA)的影响。结果降糖通脉颗粒能明显降低糖尿病家兔血糖,增加胰岛素水平,降低胰高血糖素含量,增强SOD活性,减少MDA含量。结论降糖通脉颗粒对四氧嘧啶糖尿病家兔具有明显的改善作用。Objective To observe the effects of jiangtangtongmai granule on alloxan-induced diabetes in rabbits. Methods Blood glucose, insulin, glucagons, superoxide dismutase（SOD） and malondialdedyeds（MDA） were measured through the Alloxan-induced diabetic model of rabbits. Results Jiangtangtongmai granule could significantly reduce blood glucose of alloxan-induced diabetes of rabbits, increase insulin level, reduce glucagon contents, enhance SOD activity and reduce MDA contents. Conclusions Jiangtangtongmai granule can obviously improve the alloxan-induced diabetes of rabbits.

关 键 词：降糖通脉颗粒 糖尿病 家兔 四氧嘧啶 

分 类 号：R587.1[医药卫生—内分泌]