一种治疗恒河猴婴猴菌痢的新方法  

A New Treatment for Bacillary Dysentery of Infant in Captive Macaca Mulatta Colony

作　　者：叶尤松[1] 江勤芳[1] 李春花[1] 陈瑜[1] 代成波[1] 代解杰[1] 

机构地区：[1]中国医学科学院中国协和医科大学医学生物研究所,昆明650118

出　　处：《中国比较医学杂志》2006年第11期688-690,共3页Chinese Journal of Comparative Medicine

摘　　要：目的以药物保留灌肠的综合治疗措施,观察药物对恒河猴婴猴菌痢的疗效,探索治疗猴菌痢的新方法。方法在2002年10月至2004年10月期间,我们采取复方新诺明、黄连素、地噻米松保留灌肠为主的综合治疗方案,对我所饲养的部分发病婴猴进行治疗观察。采用甲酚皂、优氯净等消毒液对环境、笼舍消毒防止疾病的蔓延。结果采用保留灌肠法治疗的病猴56只,显效者38只,占67.86%;有效者13只,占23.21%;无效5只,占8.93%;死亡3只,占5.36%。结论结合药物的性质改变给药途径可以增强其疗效,降低副作用,提高病猴的治愈率。Objective To study a new treatment for bacillary dysentery of infant in rhesus monkeys. Methods From October 2002 to October 2004, we treated the part diseased infants by keeping clysis with a compound medicines of sulfamethoxazole, cefoperazone and dexamethasone, at the same time, we sterilized cages and surrounding by tolyl hydroxide soap and Puritabs Maxi in order to prevent transmission of the disease. Results It showed that the most evident effective rate was 67.9% （38/58） ;the evident effective rate was 23.2% （13/58） ;the rate of no effect was 8.92% （5/58） ;the mortality was 5.4% （3/58）. Conclusion we concluded that this treatment can enhance the healing rate for the Bacillary dysentery of infant and reduce side effect of medicines, as compare with the former therapeutic methods.

关 键 词：保留灌肠 恒河猴 菌痢 

分 类 号：R720.597[医药卫生—急诊医学]