VitB_2、VitE联合应用防治G-6PD缺陷高胆新生儿光疗时溶血  

THE VitB_2 AND VitE COMBINED USE FOR PREVENTION OF HEMOLYSIS OF JAUNDICED INFANTS WITH G-6-PD DEFICIENCY IN PHOTOTHERAPY

作　　者：陈晓玲[1] 

机构地区：[1]广州市白云区人民医院,广东广州510500

出　　处：《现代医院》2006年第11期28-29,共2页Modern Hospitals

摘　　要：目的探讨VitB2、VitE联合防治光疗致G-6PD缺陷新生儿溶血加重疗效。方法将G-6PD缺陷需光疗治疗的新生儿随机分为VitB2、VitE干预组和对照组,测定比较总胆红素(TB)、血红蛋白(Hb)及光疗指数。结果光疗后对照组Hb下降比干预组显著,光疗指数大(均p<0·01)。结论光疗致G-6PD缺陷患儿溶血加重,VitB2、VitE干预有效。Objective To study the effect of VitB2 and vitE combined use for prevention of hemolysis of jaundiced infants with G - 6 - PD deficiency in phototherapy. Methods The neonates who received phototherapy with G -6 -PD deficiency were randomly divided into the group treated with vitamine E and vitamine B2 and control group. Total bihrubin（TB） and hemoglobin（Hb） concentrations and the indexes of phototherapy were measured and compared. Results After phototherapy, in the control group with G - 6 - PD deficiency, Hb decreased and was lower and the indexes of phototherapy was higher than in the treated group （p 〈 0.01 ）. Conclusion Phototherapy is more important part in the hemolysis of neonate with G - 6 - PD deficiency, Vitamine E and vitamine B2 can effectively alleviate the hemolysis.

关 键 词：新生儿 G-6PD缺陷 光疗 溶血 

分 类 号：R512.606[医药卫生—内科学]