运动训练对脑出血大鼠神经功能恢复的影响  

The effects of exercise training on nerve functional recovery in rats with intracerebral hemorrhage

作　　者：李红玲[1] 刘春辉[1] 葛艳萍[1] 李春岩[2] 

机构地区：[1]河北医科大学第二医院康复科,石家庄050000 [2]河北医科大学第二医院神经内科,石家庄050000

出　　处：《中华物理医学与康复杂志》2006年第10期649-652,共4页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：目的探讨运动训练对脑出血大鼠神经功能恢复的影响。方法将90只SD大鼠随机分为运动组、对照组和假手术组,每组30只。运动组和对照组应用胶原酶诱导脑出血模型,假手术组用生理盐水替代胶原酶。运动组于术后24 h开始跑笼运动训练,每天40 min,连续1个月。分别于术后3,7,14,21及28 d对3组大鼠进行姿势反射、平衡、肌力评定。结果运动组功能恢复明显好于对照组,假手术组无明显功能障碍。结论早期运动训练有助于脑出血大鼠神经功能恢复。Objective To explore the effects of exercise training （ET） on the functional recovery of nerves （NFR） in rats with intracerebral hemorrhage（ICH）. Methods Ninety Sprague-Dawley rats were randomly divided into an ET group, a control group and a sham operation group （SO group）. An ICH model was established with colla- genase in the ET and control groups, while sodium chloride was used with the SO group. The ET group exercised for 40 rain a day from 24 h to 30 d after the operation. Attitudinal reflexes, balance function and muscle strength were assessed at 24 h, 3 d, 7 d, 14 d, 21 d and 28 d after the operation. Results Compared with the control group, NFR values were increased significantly in the ET group, and there was no obvious dysfunction in the SO group. Conclusion Early ET can contribute to functional recovery after ICH.

关 键 词：脑出血 运动 康复 大鼠 

分 类 号：R455[医药卫生—运动医学] R743.34[医药卫生—治疗学]