第三代超敏TSH与TRH兴奋试验的相关性探讨  

The association between the third generation sTSH and the TRH stimulating test

作　　者：储小宏[1] 赵广碧[1] 贾丽[1] 叶志恒[1] 丛安丽[1] 吴邦庆[1] 

机构地区：[1]安徽医科大学第一附属医院内分泌科,合肥230022

出　　处：《安徽医科大学学报》2006年第5期591-592,共2页Acta Universitatis Medicinalis Anhui

摘　　要：目的探讨甲状腺疾病功能诊断中,第三代超敏TSH与TRH兴奋试验在诊断意义上相关性。方法应用第三代超敏TSH化学发光法测定121例患者的TRH兴奋试验的TSH值,了解基础TSH值与TRH兴奋试验符合情况。结果基础TSH值正常组57例中有56例TRH兴奋试验是正常反应。基础TSH值低于正常组36例中有34例无反应,2例弱反应。基础TSH值高于正常组28例中有23例强反应。结论单次第三代超敏TSH测定可以替代TRH兴奋试验。Objective To evaluate association between the third generation sTSH and the TRH stimulating test in diagnosing patients. Methods The sTSH of 121 patients in the TRH stimulating test was measured using the third generation of immunochemiluminometric assay to analyze the association between the basic TSH value and the result of the TRH stimulati sponses to the TRH ng test. Results 56 cases of the 57 subjects in the normal basic TSH group had normal restimulating test. In the subnormal basic TSH. group of 36 subjects, 34 cases had no response and 2 cases, low responses; while 23 cases had high responses in the 28 subjects with hypernormal basic TSH velue. Conclusion Single measurement of the third generation sTSH by immunochemiluminometric assay can replace the TRH stimulating test.

关 键 词：促甲状腺素/分析 甲状腺功能亢进症/诊断 化学发光测定法 

分 类 号：R335.2[医药卫生—人体生理学] R347.514[医药卫生—基础医学]