重型弥漫性轴索损伤早期处理对策  

Early therapy strategy on patients with diffuse axonal injuries

作　　者：李伯恩[1] 吴金[1] 严畅[1] 

机构地区：[1]安徽省蚌埠市第三人民医院ICU,安徽蚌埠233000

出　　处：《安徽医药》2006年第11期853-854,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的 探讨重型弥漫性轴索损伤（DAI）早期处理对策。方法 对1998年1月-2005年8月收治的重度弥漫性轴索损伤患者于伤后12h内，给予钙离子拮抗剂、亚低温治疗、控制血糖、阿片受体拮抗剂应用、防止应激性溃疡、肠内外营养支持以及合并伤早期处理，维持呼吸循环稳定。结果 伤后6个月按GOS统计，其中死亡8例，植物生存6例，重残8例，中残12例，良好8例。结论 对重型DAI早期综合治疗（12h内）可明显降低患者的死亡率和致残率。Aim To discuss the early treatment of the patients with diffuse axonal injuries（DAI）. Methods Within 12 hours after injury all the patients with DAI hospitalized from January, 1998 to Aug,2005 were treated with calcium channel blocker, mild hypothermia, glucose control, antagonist for opioid receptors, prevention of stress ulcer, parenteral nutrition and enteral nutrition, earlier period management to associated injury and maintain the stability of respiratory and circulation system. Results The prognosis of the patients was evaluated according to Glasgow Outcome Scale （GOS） six months after injury . 0f 42 patients with DAI , 8 cases were dead ,6 persistent vegetative state, 8 severe disability, 12 moderate disability, 8 good recovery. Conclusion The early period combined therapy can obviously reduce the mortality and the rate of deformity in patients with DAI.

关 键 词：重型弥漫性轴索损伤 早期综合处理 预后 

分 类 号：R651.1[医药卫生—外科学]