IDDM患者血清sIL-2R水平及临床意义  

Serum SIL—2R level of and its clinical significance in patients with IDDM

作　　者：郭军[1] 陈利明[1] 郭树森 马宏岩[2] 

机构地区：[1]佳木斯医学院第一附院 [2]佳木斯市中心医院

出　　处：《佳木斯医学院学报》1996年第5期69-70,共2页

摘　　要：本文测定了15例 IDDM 患者治疗前后血清可溶白细胞介素—2受体(sIL—2R)水平.结果发现 IDDM 患者治疗前(sIL—2R)水平显著升高,治疗后 sIL—2R 恢复至正常范围。结果提示:IDDM 患者体内存在细胞因子免疫调节紊乱,sIL—2R 可反映疾病的免疫动态.The soluble interleukin—2 receptor(SIL—2R)level was measured in 15 IDDM patients and 10 normal controls.In untreated IDDM patients,SIL—2R level was significantly elevated as com- pared to normal controls (P<0.01).Following trearment,SIL—2R level was returned gradually te normal.It was suggested that in IDDM,immune regulation of cytokines was in disorder the AIL—2R level might reflect the immune activity of IDDM.

关 键 词：糖尿病 IDDM IL-2 SIL-2R 

分 类 号：R587.1[医药卫生—内分泌]