急性心肌梗塞静脉溶栓疗法的临床观察  

Clinical observation of thrombolytic therapy in acute myocardial infarction

作　　者：费宇行[1] 石湘芸[1] 熊鑑然 高连如[1] 徐洪涛[1] 田慧生[1] 

机构地区：[1]海军总医院心内科

出　　处：《海军总医院学报》1996年第3期151-154,共4页Journal of Naval General Hospital of PLA

摘　　要：我科于91年4月至95年2月用静脉血栓溶解疗法治疗急性心肌梗塞(AMI)27例,男性21例,女性6例,年龄40~70岁,平均58±7岁,用药后2小时内梗塞相关血管再通12例,再通组发病至溶栓开始的平均时间214±54Min,较未通组328±83min短,差异有显著意义(P<0.05),再通组治疗2h内发生快速心律失常7例,占73%,较未通组27%高(0.05<P<0.01),血管再通组左室射血分数(EF)为58%.较未通组44%高,差异有显著意义(P<0.05),全部病例死亡3例,死亡率11%,未通组死亡2例,两组均无大出血并发症出现,治疗结果示此疗法对AMI是有效、安全的治疗方法.27 patients with acute myocardial infarction (AMI) have been treated by intrave-neos thrombolytic therapy. Among them, 21 were male and 6 female, aged from 40 to 70 yearsold (average 57+/-7). There were 13 cases with the recanalization of infarct-related arterieswithin two hours after the treatment of thrombolysis. The average time from onset of AMI tostart of the treatment of thrombolysis was 214 +/-54 minuts It was significantly earlier thanthat with no recanalizing patients (P<0. 05). In the recanalization group, the frequancy of rapidarrythmia was 73%, compared with 27% in the group without recanalization (X2= 3. 04). LVEFwas measured using echocardiography after 4 weeks of the treatment or before discharge from hos-pital. In the recanalization group the EF was 58%, it was significantly better than that of anothergroup. There were 3 death cases, including two cases without recanalization. The mortality was11%. There was no case with massive bleeding. The result showed that this method was an effec-tive and relative-safety therapy for patients with AMI.

关 键 词：急性 心肌梗塞 溶栓疗法 

分 类 号：R542.220.5[医药卫生—心血管疾病]