细胞粘附分子在老年陈旧心肌梗死空气净化前后的变化  

Effects of air cleaning on sICAM-1 and sVCAM-1 in elderly patients with old myocardial infarction

作　　者：连芳[1] 

机构地区：[1]河南第一荣康医院,河南新乡453003

出　　处：《中国民康医学》2006年第21期934-935,共2页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨空气净化对老年陈旧性心肌梗死患者血清可溶性细胞间粘附分子-1(sICAM-1)和可溶性血管细胞粘附分子-1(sVCAM-1)表达的影响。方法:老年陈旧性心肌梗死(OM I)疗养员99例随机分为空气净化组(n=54)和未净化组(n=45),另选20人为健康对照组。空气净化组所处的疗养室进行24 h空气净化,未净化组和对照组住普通病房,不进行空气净化。住院时和住院后1个月抽血,应用流式细胞仪检测血清可溶性细胞间粘附分子-1(sICAM-1)、可溶性血管细胞间粘附分子-1(sVCAM-1)。结果:空气净化1个月后,患者sICAM-1和sVCAM-1均显著下降(P<0.05)。结论:对OM I患者行空气净化治疗,能显著改善其sICAM-1和sVCAM-1,使病情得到改善。Objective：To study the effects of air cleaning on serum soluble intercellular adhesion molecule - 1 （ sICAM - 1 ） and soluble vascular cell adhesion molecule - 1 （ sVCAM - 1 ） in elderly patients with old myocardial infarction. Methods ： The air of houseroom lived in 54 elderly patients with old myocardial infarction were cleansed for 24h one day, and tested the sICAM - 1 and sV- CAM - 1 after 1 month. Results： The sICAM - 1 and sVCAM - 1 was markedly decreased. Conclusions ： The therapy of air cleaning can markedly improve the sICAM - 1 and sVCAM - 1 of elderly patients with old myocardial infarction.

关 键 词：可溶性细胞间粘附分子-1 可溶性血管细胞粘附分子-1 陈旧性心肌梗死 空气净化 老年人 

分 类 号：R542.22[医药卫生—心血管疾病]