氟中毒与自由基及某些微量元素的关系  

Progress of study on free radical mechanism of fluorosis in China

作　　者：张妍[1] 

机构地区：[1]中国预防医学科学院环境卫生与卫生工程研究所

出　　处：《卫生研究》1996年第4期216-220,共5页Journal of Hygiene Research

摘　　要：对氟中毒的自由基机制、氟中毒所引起的患者体内微量元素的变化做了综述。氟可导致体内脂质过氧化水平升高。但氟如何导致脂质过氧化水平改变，即氟是直接参与自由基链式反应，还是通过影响到微量元素水平，或者以其它方式改变脂质过氧化水平。he authors summerized the free radical mechanism of fluoride poisoning and the changes of trace element in fluorosis patients caused by fluoride . It is proved that fluoride can cause high level of lipid peroxidation in vivo. However, how fluoride increases lipid peroxidation (whether fluoride directly interferes with the chainreaction of free radical, or affects by the way of changing the level of trace element, or through some other mechanisms ) would be an urgent problem in the study of human fluorosis.

关 键 词：氟中毒 微量元素 自由基 

分 类 号：R599.902[医药卫生—内科学]