神经妥乐平治疗糖尿病神经病变的研究  

CLINICAL STUDY OF THE EFFECTS OF NEROTROPIN ON DIABETIC NEUROPATHY

作　　者：李金荣[1] 李静波[1] 相莉[1] 

机构地区：[1]天津市人民医院内分泌科,天津300131

出　　处：《中国疼痛医学杂志》2006年第5期291-293,共3页Chinese Journal of Pain Medicine

摘　　要：目的:评价神经妥乐平治疗2型糖尿病周围神经病变的疗效。方法:74例糖尿病神经病变患者随机进入神经妥乐平组(38例)和胰激肽原酶组(36例)。神经妥乐平组每天1次静脉点滴神经妥乐平针,每次2支(3.6 u/支),14天后口服神经妥乐平片,每次2片,每天2次,共14天。胰激肽原酶组每天1次肌肉注射胰激肽原酶针,每次2支(10 u/支),14天后口服胰激肽厚酶肠溶片,每次2片,每日三次,共14天。结果:治疗后,两组的感觉VAS评分皆有明显降低。疼痛改善神经妥乐平组显效率及总有效率明显高于胰激肽原酶组。神经妥乐平组麻木感改善显效率明显高于胰激肽原酶组。结论:神经妥乐平对2型糖尿病神经损害的自发性疼痛,感觉障碍有较好疗效。Objective： To estimate the effects of Neurotropin in the treatment of neuralgia and numbness in type Ⅱ diabetes mellitus patients with peripheral neuropathy （DPN）. Methods ：74 patients with DPN were randomly assigned to two groups ：38 cases in Neurotropin group （7.2 U, IV, QD for 14 days, then 2 tablets, BID for another 14 days） , 36 cases in Pancreatic kininogenase group （20 U, IM, QD for 14 days, then, 2 tablets, TID for another 14 days）. Results：The VAS scores were decreased in two groups after 28 days treatment. Neuralgia and numbness were improved in the two groups, and the improved rate in Neurotropin group was high than that in the control group. Conlusion： Neurotropin had good effects in the treatment of diabetic neuralgia and numbness.

关 键 词：糖尿病神经病变 疼痛 神经妥乐平 胰激肽原酶 

分 类 号：R587.2[医药卫生—内分泌]