功能性磁刺激治疗神经原性膀胱的疗效追踪(英文)  

Effect of functional magnetic stimulation on the treatment of neurogenic bladder

作　　者：周宁[1] 陆敏[1] 黄晓琳[1] 丁新华[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院康复医学科,湖北省武汉市430030

出　　处：《中国临床康复》2006年第44期190-192,共3页Chinese Journal of Clinical Rehabilitation

基　　金：湖北省科技攻关计划项目(2003AA301C111)~~

摘　　要：背景:功能性磁刺激具有安全、无创、无副作用等优点,目前已逐步用于中枢神经传导、疲劳恢复、骨愈合、神经疾病治疗及脑功能研究等各方面,且能改善排尿功能障碍患者的症状。目的:追踪观察功能性磁刺激治疗神经原性膀胱的疗效。设计:自身前后对照实验。单位:华中科技大学同济医学院附属同济医院康复医学科。对象:选择2003-06/2004-06在华中科技大学同济医学院附属同济医院康复医学科住院及泌尿外科就诊的20例神经原性膀胱患者,其中脊髓损伤造成神经原性膀胱12例,其他原因所致的神经原性膀胱8例。方法:采用Dantec公司(丹麦)生产的MagLite型磁刺激仪,经S3神经根和膀胱区的功能性磁刺激治疗,参数设置:强度为70%～80%最大磁强度;频率为5Hz;脉冲长度为1ms。连续磁刺激20次,休息2s,5min/次,2次/d,5d/周,4～6周为1个疗程。主要观察指标:治疗前、治疗后、停止治疗后1,3个月观察以下指标:①排尿次数、平均单次尿量及单次最大排尿量。②因排尿的症状而影响生活质量评分:评分范围为0～6分,得分越高生活质量越差。③国际下尿路综合征症状评分:共7个问题,总分0～35分,得分越高症状越重。结果:20例患者全部进入结果分析。①因排尿的症状而影响生活质量评分:治疗后较治疗前显著下降(3.17±1.53,4.58±1.00,P<0.01),停止治疗后1,3个月虽有上升,但仍低于治疗前(P<0.01)。②国际下尿路综合征症状评分:治疗后较治疗前显著下降(21.42±5.00,28.08±1.51,P<0.01),停止治疗后1,3个月虽有上升,但仍低于治疗前(P<0.01)。③治疗后排尿次数明显减少,平均单次尿量和单次最大排尿量增加(P<0.05);停止治疗1个月,各项指标下降,但仍优于治疗前(P<0.05);停止治疗3个月虽各项指标继续下降,但除平均单次尿量与治疗前比较差异无显著性意义(P>0.05),其余各项仍优于治疗前(P<0.05),且治疗后各时间�BACKGROUND： Functional magnetic stimulation （FMS） is characterized by safe, unwounded and non-side effect. At present, it has been used in central nervous conduction, recovery from nerVous exhaustion, bone healing, treatment of neural disorder, research of brain function, and so on; meanwhile, it also can improve urination dysfunction. OBJECTIVE： To pursue investigating the effect of FMS on the treatment of neurogenic bladder. DESIGN： Self controlled study pre- and post-treatment. SETTTNG： Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technique. PARTICIPANTS： Twenty patients with neurogenic bladder were recruited in the Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technique from June 2003 to June 2004. Of them, 12 patients with neurogenic bladder were caused by spinal cord injury and 8 by other reasons under urinary dynamic examinations. METHODS： Twenty patients with neurogenic bladder underwent S3 never root and bladder FMS by MagLite magnetic stimulation system （Dantec Company, Denmark）, for 20 successive times, twice a day, five days a week and 4-6 weeks as a course. The interval was 2 seconds and the frequency was 5 minutes for once. Parameters were designed as the following： intensity： 70%-80% maximal magnetic intensity; frequency： 5 Hz; impulse length： 1 ms. MAIN OUTCOME MEASURES： Parameters were observed pretreatment, post-treatment immediately and at 1 and 3 months： （1） Urine frequency： the mean voided volume and the maximal voided volume; （2） Scores of quality of life （QOL）： Scores ranged from 0 to 6 points. The higher the scores were, the poorer the QOL was. （3） International lower urinary tract symptoms （LUTS） scores： There were 7 questions with the scores of 0-35. The higher the scores were, the severer the symptoms were. RESULTS： All 20 patients were involved in the final analysis. （1） Eff

关 键 词：磁疗法 膀胱 神经原性 排尿障碍 

分 类 号：R454.1[医药卫生—治疗学]