^(99m)Tc-MIBI心肌灌注断层显像评价心肌梗死后左室重构  

Quantitative evaluation of left ventricular remodeling using ^(99m)Tc-MIBI myocardial SPECT imaging for patients with myocardial infarction

作　　者：张居洋[1] 王跃涛[1] 鹿存芝[1] 朱峰[1] 王冠民[1] 傅宁[1] 

机构地区：[1]东南大学医学院附属徐州医院核医学科,江苏徐州221009

出　　处：《东南大学学报（医学版）》2006年第6期434-436,共3页Journal of Southeast University(Medical Science Edition)

摘　　要：目的:应用99mTc-甲氧异丁基异腈(M IB I)心肌灌注显像对左室重构进行半定量评估。方法:随机从99mTc-M IB I心肌灌注显像库中抽取心肌梗死患者55例,其中前壁组25例,下后壁组30例;正常对照组30例。采用自编软件测定前壁或下后壁梗死部位局部膨出指标EG/EF或FG/EF值、左室心肌梗死后球形化指标EF/AB值。结果:前壁组EG/EF值明显高于正常组,下后壁组FG/EF值与正常组无明显差别。前壁组、下后壁组EF/AB值均明显高于正常组,前壁组EF/AB值明显高于下后壁组。结论:心肌灌注断层显像的半定量指标EG/EF、FG/EF和EF/AB可用于心肌梗死后左室重构的评价。Objective To quantitatively evaluate left ventricular remodeling（LVRM） using ^99mTc-MIBI myocardial SPECT imaging. Methods 55 patients randomly sampling from ^99mTc-MIBI myocardial SPECT imaging database,were divided into two groups according to different infarction locums：25 patients with interior,30 patients with inferoposterior. 30 volunteers enrolled in this study as normal control. The value of EG/EF or FG/EF and the value of EF/AB were measured by a program made by ourselves. Results The value of EG/EF in patients with interior infarction were significantly higher than those in normal group, the values of FG/EF in patients with inferoposterior infarction and those in normal group had no significantly difference. The value of EF/AB in patients with interior wall group and the inferoposterior group were significantly higher than those in normal group, and in patients with myocardial infarction, the values of interior wall group were significantly higher than those in inferoposterior group. Conclusion EG/EF or FG/EF and EF/AB may be used to quantitatively evaluate LVRM after myocardial infarction.

关 键 词：甲氧异丁基异腈 放射性核素显像 心肌梗死 左室重构 

分 类 号：R817.4[医药卫生—影像医学与核医学] R541.4[医药卫生—放射医学]