汕头市2003-2005年健康人群麻疹抗体水平分析  

Analysis of Anti-Measels Antibody in the Healthy Population in Shantou City in 2003-2005

作　　者：黄建晖[1] 黄少珊 郭昕东 蔡咏娜 

机构地区：[1]汕头市疾病预防控制中心,汕头515000

出　　处：《热带医学杂志》2006年第11期1194-1196,共3页Journal of Tropical Medicine

摘　　要：目的了解汕头市麻疹疫苗(MV)接种效果和人群麻疹抗体水平。方法连续3年每年1个监测点,每个监测点随机抽取2～4岁、6～8岁、13～15岁健康人群各约60人,应用酶联免疫吸附试验检测麻疹IgG抗体。结果540人中抗体阳性526人,阳性率97.41%,几何平均滴度(GMT)1∶1441.99;444人抗体滴度达到保护水平,保护率为82.22%。各年龄组之间的GMT差别无统计学意义;各年(各监测点)之间的GMT差别有显著的统计学意义,但各监测点之间麻疹疫苗接种率差别无统计学意义。结论计划免疫运作方式与麻疹抗体水平存在一定的关系,在规范化预防接种门诊内进行接种是获得良好的免疫效果的关键。Objective To determine the efficacy of measels vaccine （MV） and the levels of anti-measels antibody in individuals after primary and supplementary immunization of MV in Shantou city. Methods This study was performed at 3 randomly selected monitoring stations, one station per year, for 3 consecutive years. The level of antimeasels antibody was measured in 60 healthy individuals from each age group （2-4; 6-8; and 13-15 years of age）. Results 97.41% （526 out of 540） of the individuals was sero-positive for measles. The geometric mean titres （GMT） for the anti-measels antibody was 1：1441.99. The antibody titres in 444 individuals reached a protective level, and the protecting rate was 82.22%. The difference among each age group was not significant. However, the results obtained from each monitoring station were significantly difference. Conclusion The differences in the results obtained from these 3 monitoring stations may be due to the different mode of operation of these stations. It is important to standardize the immunization in the clinic.

关 键 词：麻疹 免疫 抗体水平 健康人群 汕头市 

分 类 号：R511.1[医药卫生—内科学]