降钙素原在新生儿细菌感染中的诊断价值  

Diagnostic value of procalciton on neonatal bacterial infectious diseases

作　　者：朱建央[1] 李永昕[1] 朱亚非[1] 

机构地区：[1]温州医学院附属第五医院浙江省丽水市中心医院儿科,323000

出　　处：《中国新生儿科杂志》2006年第5期261-264,共4页Chinese Journal of Neonatology

摘　　要：目的探讨降钙素原(PCT)在新生儿重症感染时的诊断价值。方法将167例住院新生儿分严重感染组、一般感染组、非感染组、恢复期组4组,检测血清PCT、血清CRP、白细胞计数及分类,进行结果分析。结果以PCT≥0·5ng/ml为阳性,各组阳性:重感染组为88·00%,一般感染组为55·00%,非感染组为14·29%,恢复期组为9·52%,严感染组阳性率明显高于其他3组与3组间两两比较,差异有统计学意义(Hc=73·24,P<0·00)。结论PCT可作为新生儿感染的早期检测指标,动态检测PCT可判断疗效及预后。Objective To evaluate the diagnostic value of procalciton （PCT） on neonatal bacterial infectious diseases. Methods One hundred and sixty-seven hospitalized neonates were divided into 4 groups, severe infection group, common infection group, non-infection group and severe infection recovery group, according to their clinical conditions and basic laboratory study. Their serum PCT, CRP, white blood cell count and differentiation were tested. Results Serum PCT≥0. 5ng/ml was considered as positive. The positive rate was 88.0% in severe infection group, 55.0% in common infection group, 14. 3% in non-infection group, and 9. 5% in severe infection recovery group, respectively. The positive rate of PCT in severe infection group was significantly higher than that in other 3 groups, Hc = 73. 24, P 〈 0. 00. Conclusions PCT is a high sensitive and specific parameter in the early diagnosis of neonatal bacterial infection, and dynamic detection of PCT can be used to evaluate curative effect and prognosis.

关 键 词：降钙素 婴儿 新生 细菌感染 

分 类 号：R722.1[医药卫生—儿科]