均匀设计法优选固本止咳膏的水煮提取工艺  

Optimization of the Water Extractive Process for Guben Zhike Electuary with Uniform Design

作　　者：孔桂豪[1] 李嘉[2] 伦丽雄 邓汝铭[1] 黄瑞松[1] 

机构地区：[1]中国中医科学院广西民族医药研究所,广西南宁530001 [2]广西中医药研究所,广西南宁530022 [3]瑞福祥药业(广西)有限公司,广西梧州543003

出　　处：《中国中医药信息杂志》2006年第11期61-62,85,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：广西科技厅攻关课题(9635088)

摘　　要：目的优选固本止咳膏的水煎煮提取工艺。方法用均匀设计的方法安排实验,以多糖含量及黄芪甲苷含量为考核指标,考察煎煮次数、煎煮时间及加水量对上述有效成分提取率的影响,优选合理的提取工艺。结果以水为溶剂,煎煮3次,每次煎煮2h,每次加水量为药材用量的9倍为最佳提取工艺。结论优选出的最佳工艺可提取出药材中大部分的有效成分,此工艺是科学的。Objective To optimize the water extractive process of Guben Zhike Electuary. Methods To arrange experiments with uniform design for optimizing suitable extractive proces, with the content of polysaccharide and astragaloside IV as the detecting indexes, inspecting the extacting times, lasting time and additional water which would affect the extraction rate of the two effective components. Result The best process was that water as extraction solvent, extracted for three times with two hours each time, and the amount of water added up to nine times of herbs. Conclusion The best process could extract most of the effective components out of the herbs, which is scientific.

关 键 词：固本止咳膏 提取工艺 均匀设计 

分 类 号：R283.5[医药卫生—中药学]