生活事件对功能性消化不良患者精神心理状况和疾病的影响  

The Effects of Life Events to the Psychological Status and Disease in Functional Dyspepsia patients

作　　者：曹佳懿[1] 郭锐[1] 熊汉华[1] 侯晓华[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院消化科

出　　处：《临床内科杂志》2006年第11期742-744,共3页Journal of Clinical Internal Medicine

摘　　要：目的探讨功能性消化不良(FD)患者生活事件、心理异常状况以及它们与症状间的关系。方法对114例FD患者和100例对照组进行Zung焦虑自评量表、Zung抑郁自评量表和生活事件量表的问卷调查,对FD患者进行症状评分,然后分析比较。结果(1)FD患者经历的生活事件总值(P=0.014)和负性生活事件值(P<0.001)均高于对照组,正性生活事件值低于对照组(P=0.001);(2)FD患者焦虑、抑郁发生率(P<0.005)和平均焦虑、抑郁程度均高于对照组(P<0.001);(3)FD患者的症状积分与生活事件值无相关性;(4)FD患者的生活事件总值和负性生活事件值与焦虑(P<0.01)、抑郁程度(P<0.05)均呈正相关,正性生活事件值则与它们无相关性。结论患者经历过更多的负性生活事件是FD的特征和诱因之一,它可能通过诱发患者的精神心理因素异常而影响FD的发生发展。Objectives To explore the experience of life events and psychological abnormalities in patients with functional dyspepsia （ FD）, and the relationship with symptoms. Methods A question- naire study for 114 FD patients and 100 healthy volunteers included the Symptom Scale,Zung Self-Rating Anxiety Scale （SAS） ,Zung Self-rating Depression Scale （SDS） ,and the life event scale （LES）. All the scales were analyzed in comparisons of each other. Results 1. The total scores of life events and the scores of negative life events in patients with FD were higher than those of healthy group （ P = 0.014 and P 〈 0.001 ）, but the favorable life events scores were lower than those of healthy group（ P = 0. 001 ）. 2. The incidence of anxiety and depression in patients with FD was higher than that in healthy volunteers, and the average extent of anxiety and depression of their was significantly higher than that in healthy people（ P 〈 0.001 ）. 3. In the FD patients, there was no significant correlation between the evaluation of symptoms and life events. 4. There were positive correlation among the total scores of life events, negative life events scores and anxiety evaluation of the FD patients （ P 〈 0.01 ）, and also with depression evaluation （ P 〈 0.05）, there was no significant correlation among the favorable life events scores with anxiety and depression evaluation both. Conclusion experiencingmore negative life events was one of the character and inducement of FD patients, it may influence the occurrence and evolution of FD by inducing psychological abnormity of these patients.

关 键 词：功能性消化不良 生活事件 心理因素 

分 类 号：R395[哲学宗教—心理学]