肝移植术后乙肝复发的临床特点分析  

ANALYSIS OF THE HEPATITIS B RECURRENCE AFTER LIVER TRANSPLANTATION

作　　者：蒋力[1] 穆毅[1] 黄容洚[1] 赵凤林[1] 李传胜[1] 鲁岩[1] 赫荣[1] 毛羽[1] 

机构地区：[1]北京地坛医院,北京100011

出　　处：《肝胆外科杂志》2006年第5期366-368,共3页Journal of Hepatobiliary Surgery

摘　　要：目的探讨肝移植术后乙肝复发的特点和治疗的可行性。方法回顾性分析2例肝移植术后乙肝复发病例和1例移植后早期血清HBsAg(+)、HBV-DNA(+)病例的临床诊疗经过,分析比较肝移植术后乙肝复发的临床特点。结果2例肝移植乙肝复发病例治疗后乙肝病毒未能清除,1例移植后早期血清HBsAg(+)、HBV-DNA(+)病例治疗后乙肝病清除。结论肝移植术后乙型肝炎病毒变异和肝移植术前高病毒量是移植术后乙肝复发的重要原因;移植术后及时的病理能够提示抗病毒治疗结果。Object To discuss the hepatitis B recurrence＇s characteristics and treatment feasibility after liver transplantation through the treatment of clinical recurrent cases. Method Analyze retospectively 2 cases of hepatitis B with recurrence after liver transplantation and 1 case of early phas after transplantation with serum HBsAg （ ＋ ）, HBV - DNA （ ＋ ）, to analyze and compare the clinical characteristics of hepatitis B recurrence after liver transplantation. Result HBV were not eliminated after liver transplantation in two patients of hepatitis B with recurrence; one patient＇s HBV were eliminated early phase serum HBsAg（ ＋ ） ,HBV -DNA（ ＋ ）after transplantation. Conclusion HBV variation and high virus quantum before liver transplantation are main factors causing the recurrence of hepatitis B after transplantation; timely pathological examination after transplntation could indicate the anti - virus treatment result.

关 键 词：肝移植 肝炎 乙型 复发 

分 类 号：R657.3[医药卫生—外科学]