新生儿败血症血培养分离菌及耐药性分析  

Pathogens and Antibiotic Resistance of Lsolates from Newborn Septicemia Biood Cultures

作　　者：唐任光[1] 杨显先[1] 龙显科[1] 

机构地区：[1]右江民族医学院附属医院,广西百色533000

出　　处：《实用医技杂志》2006年第20期3533-3535,共3页Journal of Practical Medical Techniques

摘　　要：目的:了解我院近期新生儿败血症病原菌及耐药性,为临床用药提供依据。方法:对我院2001年1月至2006年1月新生儿血培养阳性标本细菌鉴定及药敏结果进行分析总结。结果:251例阳性标本中表皮葡萄球菌和金黄色葡萄球菌分别占31.5%和16.7%,对多种抗生素耐药,苯唑西林的耐药率分别为87.5%、62.6%,对万古霉素100%敏感;革兰阴性菌中大肠埃希菌占首位,其次为肺炎克雷伯杆菌、肠杆菌属、普通变形杆菌;抗菌活性较好的药物是阿米卡星、环丙沙星、氧氟沙星。结论:葡萄球菌是新生儿败血症的主要病原菌;临床医师应根据细菌鉴定及药敏试验选择敏感药物治疗。Objective To understand the distribution of pathogens causing newborn septicemia and their antibiotic resistance . Methods The positive in blood culture of newborn in our hospital between January, 2001 and January, 2006 were analyzed. Results Among 251 positive in blood culture, positiveratio of Staphylococcus epidermidis and S. aureus were 31.5 % and 16.7 %, respectively. Furthermore, they were muhiresistant. The ratio of meticillinresistant S. epider midis and S. aureus were 87.5% and 62.6%, respectively, but all were sensitive to vancomycin. Among gram-negative bacteria,Escherichia coil was in the first place, the second one was klebsiella pneumonniae, the other were Enterobacter, proteus vulgaris . The better antibiotics for them were amikacin,ciprofloxacin, and ofloxacin. Conclusion Staphylococcus spp is one of the main pathogens causing newborn septicemia, The identification of bacteria and drug sensitive test were helpful to clinical therapy.

关 键 词：新生儿败血症 病原菌 耐药性 

分 类 号：R722.1[医药卫生—儿科] R446.5[医药卫生—临床医学]