辅助生殖技术结局的临床相关因素分析  

Pregnant outcome and variables affecting success in IVF/ICSI

作　　者：巫新春[1] 曹云霞[1] 丛林[1] 魏兆莲[1] 周平[1] 赵济华[1] 李芬[1] 章志国[1] 张文香[1] 

机构地区：[1]安徽医科大学第一附属医院妇产科生殖医学中心,安徽合肥230022

出　　处：《中国妇幼保健》2006年第21期3003-3005,共3页Maternal and Child Health Care of China

摘　　要：目的：回顾分析辅助生殖技术（IVF／ICSI）中妊娠结局，并对临床相关因素及其对妊娠结局的影响进行分析。方法：收集我院生殖中心2004年1月1日-6月31日176例患者189个辅助生殖周期治疗的临床资料，进行整理统计和分析。结果：种植率、生化妊娠率及临床妊娠率分别为22．97％、33．53％、30．64％；冻融胚胎移植临床妊娠率23．08％，单周期累计临床妊娠率32．37％；妊娠者较未妊娠者年龄轻（P〈0．05）；年龄≤35岁组较年龄〉35岁组妊娠率高（分别为48．98％和11．11％，P〈0．05）；妊娠史对治疗结局有一定影响。结论：分析IVF／ICSI中影响妊娠结局的临床相关因素将提高种植率和妊娠率。Objective： To analyze the pregnancy outcome of in vitro fertilization （IVF） /intracytoplasmic sperm injection （ICSI） and evaluate the variables ＇affecting embryo transfer success or failure. Methods ： A retrospective cohort study was conducted. The population under study consisted of 176 consective fresh embryo transfers and 13 frozen embryo transfers. Results： Implantation and clinical pregnancy rates were 22. 97% and 30. 64% respectively, and the clinical pregnancy rates of frozen embryo transfer were 23. 08% which resulted in a cumulative clinical pregnancy rates per cycle of 32. 37%. The pregnancy rates were significantly increased in ≤35 years old group compared to that in 〉 35 years old group （48. 98% vs 11. 11% , P 〈 0. 05）. The patients who had historic pregnancy would affect the preg- nancy outcome in subsequent IVF. Conclusion： An understanding of variables associated with embryo transfer success will enhance the efficiency of IVF/ICSI by maximizing embryo implantation.

关 键 词：妊娠结局 辅助生殖 临床因素 

分 类 号：R715.9[医药卫生—妇产科学]