附睾精子和睾丸精子妊娠结局比较  

The pregnancy outcome of treatment on azoospermia patients with epididymal or testiclular sperm.

作　　者：刘雅峰[1] 欧建平[1] 王琼[1] 周灿权[1] 

机构地区：[1]中山大学附属第一医院生殖医学中心,广州510080

出　　处：《中国优生与遗传杂志》2006年第11期100-101,共2页Chinese Journal of Birth Health & Heredity

基　　金：2004年度广东省自然科学基金博士启动基金(课题号:04300344)

摘　　要：目的比较经皮附睾穿刺抽吸术和经皮睾丸精子抽吸术两种方法获得的精子妊娠结局。方法83例无精子症患者经皮附睾穿刺抽吸术取得附睾精子;35例无精子症患者经皮睾丸精子抽吸术(TESA)获得睾丸精子。女方进行常规超排卵。采用卵胞浆内单精子注射技术获得妊娠,比较两者的受精率、种植率和临床妊娠率。结果附睾精子组和睾丸精子组的受精率分别为75.20%和74.61%,比较其差异无显著性(P>0.05);两者的种植率和临床妊娠率分别为29.18%vs23.89%和52.43%vs 40.21%,差异具有显著性(P<0.05)。结论附睾是精子获能、成熟的重要部位,附睾精子优于睾丸精子,对无精子症患者行ICSI之前尽可能首先选取附睾精子。Objective： To compare the pregnancy outcome of treatment on azoospermia patients with epididymis or testicle sperm Metheds： All patients were undergone sperm retrieval by percutaneous epididymal sperm aspiration （PESA） or testitucular sperm aspiration （TESA）. They accepted ICSI for treatment of azoospermia. The rates of fertilization, implantation and pregnancy were analyzed and evaluated. Results： Sperm were retrieved by PESA in 83 of 118 and by TESA in 35 of 118 men of azoospermia. The fertilization rate, implantation and clinical pregnancy rate were 75.20%%, 29. 18% and 52.43%, respectivetively, in PESA group, and 74. 61%, 23. 89% and 40. 21%, respectively, in TESA group. The fertilization rates of two groups were different （ P 〈0. 05） ; The implantation and clinical pregnancy rates were similar （ P 〉 0. 05 ）. Conclusions ： Epididymis is the important position of capacitation and spermiotelcosis. Epididymal sperm shoud be choosen first for ICSI.

关 键 词：无精子症 附睾精子 睾丸精子 卵胞质内单精子注射 

分 类 号：R714.8[医药卫生—妇产科学]