3-硝基-4-甲氧基乙酰苯胺的选择性催化加氢  

Selective Catalytic Hydrogenation of 3-Nitro-4-methoxyacetanilide

作　　者：马荣华[1] 胡爽[1] 辛俊娜[1] 侯洁[1] 郭方[1] 吕荣文[1] 吕连海[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,辽宁大连116012

出　　处：《精细化工》2006年第11期1138-1141,共4页Fine Chemicals

基　　金：辽宁省自然科学基金(No:20052188)~~

摘　　要：以改性骨架镍为催化剂,催化3-硝基-4-甲氧基乙酰苯胺(NMA)液相选择加氢制备了3-氨基-4-甲氧基乙酰苯胺(AMA)。在反应温度60℃,压力0.15 MPa,m(催化剂)/m(NMA)=1/10时,反应1 h,NMA转化率为100%,AMA的选择性达99.9%。分别以乙醇和甲醇为溶剂考察了催化剂的寿命,在乙醇中催化剂连续套用42次,转化率均为100%,AMA选择性只由99.2%下降到97.0%;在甲醇中连续套用15次,转化率均为100%,AMA选择性均高于99.5%。Modified skeletal Ni catalyst was used in liquid phase selective hydrogenation of 3-nitro-4-methoxyacetanilide （NMA） to prepare 3-amino-4-methoxyacetanilide （AMA）. The conversion was 100% and the selectivity was up to 99. 9% under the conditions of 60℃ ,0. 15 MPa, 1 h and m （catalyst） ：m（NMA） = 1：10. The catalyst showed excellent performance in either ethanol or methanol. When the catalyst was repeatedly used for 42 times in ethanol,the conversion of NMA retained 100% and the selectivity of AMA decreased only times in methanol, the conversion retained 99.5%. to 97.0% from 99.2%. When the catalyst was used for 15 100% and the selectivity of AMA was always higher than

关 键 词：改性骨架镍 3-硝基-4-甲氧基乙酰苯胺 催化加氢 3-氨基4-甲氧基乙酰苯胺 

分 类 号：TQ031.4[化学工程] O643.3[理学—物理化学]