2型糖尿病合并外周血管病变患者的骨密度变化  

Changes of bone mineral density in type 2 diabetes mellitus with peripheral vessel disease

作　　者：侯建明[1] 李建卫[1] 林庆明[1] 陈文新[1] 庄维特[1] 蔡穗珍[1] 张超群[1] 林丽香[1] 

机构地区：[1]福建省立医院福建医科大学省立临床医学院内分泌科,福州350001

出　　处：《中国医师进修杂志（内科版）》2006年第11期46-48,共3页Chinese Journal of Postgraduates of Medicine

基　　金：福建省自然科学基金计划资助项目(C0410041)

摘　　要：目的探讨2型糖尿病合并外周血管病变患者的骨密度变化。方法将100例2型糖尿病患者分为无并发症组(A组)和合并外周血管病变组(B组),进行双能X线吸收法(DEXA)骨密度(BMD)测定,同时测定臂踝脉波传播速度(baPWV)及超声波颈动脉内膜-中层厚度(IMT),并对两组患者临床数据与骨密度进行比较。结果2型糖尿病患者BMD低于同龄的非糖尿病患者;2型糖尿病合并外周血管病变患者BMD低于同年龄的2型糖尿病患者。结论2型糖尿病合并外周血管病变患者的动脉硬化可能与骨质疏松有关,二者的明确因果关系有待进一步研究。Objective To investigate the changes between type 2 diabetes mellitus（T2DM） with peripheral vessel disease and osteoporosis. Methods A total of 100 eases T2DM patients were divided into non -peripheral vessel disease （A group） and peripheral vessel disease （B group）. B -mode ultrasonography to measure the intima- media thickness （IMT） of carotid artery, dual energy X- ray absorptiometry （DEXA） to measured bone mineral density（BMD） and VS- 1000 arteriosclerosis diagnometer to measure braehi -ankle pulse wave velocity （baPWV） were used in 100 T2DM patients. The clinical data and BMD were compared between two groups. Results Compared with normal group, the BMD in T2DM patients significantly decreased. Compared with T2DM patients without peripheral vessel disease, the BMD decreased in T2DM patients with peripheral vessel disease. Conclusions Atheroselerosis in T2DM with peripheral vessel disease is probably related to osteoporosis, and the relationship between them is worth further investigation.

关 键 词：2型糖尿病 外周血管病变 骨密度 

分 类 号：R587.1[医药卫生—内分泌]