家兔肠缺血再灌注对膈肌电生理特性的影响  

Effect of ischemia-reperfusion injury of diaphragmatic muscle in rabbits

作　　者：台晓燕[1] 徐涛[1] 王金花[1] 聂鑫[1] 杨丽丽[1] 

机构地区：[1]蚌埠医学院临床医学系,2002年级安徽蚌埠233030

出　　处：《蚌埠医学院学报》2006年第6期603-604,共2页Journal of Bengbu Medical College

摘　　要：目的:观察家兔肠缺血再灌注对膈肌电生理特性的影响。方法:取家兔12只,随机分对照组、模型组,每组6只。复制家兔肠系膜动脉缺血再灌注损伤动物模型,测定缺血前、缺血1h及再灌注1h、2h膈肌肌电图(EMGdi),经计算机MedLab采样、数字化,快速富利叶转换(FFT)分析,计算高频/低频(H/L)比值和中心频率(Fc),数据作方差分析q检验。结果:实验组在肠缺血再灌注后1h和2h时Fc明显降低(P<0.01)。结论:肠缺血再灌注可降低膈肌肌电的Fc。Objective： To observe the effect of ischemia-reperfusion on the electrophyiology of diaphragm atic muscle in rabbits. Methods ：Twelve healthy adult rabbits were randomly divided into experimental and control groups（ each of six rabbits）. The ischemiareperfusion injury animal model was produced in rabbits . The diaphragmatic electromyogram（EMGdi） was recorded by computer. The contents of the high/low（H/L） frequency ratio and central frequency（Fc） were detected by Fast Fourier Transform（FFT） at the times of preischemia,post-ischemia and post-reperfusion. Data were analysed by variance analysis and q test. Results：The Fc in experimental group were significantly lower than that of control group （ P 〈 0.01 ） at one hour and two hours after ischemia-reperfusion injury. Conclusions：The electro-activity of diaphragm has been injuried by iscbemia-reperfusion.

关 键 词：膈/生理学 电生理学 肠系膜动脉 再灌注损伤 

分 类 号：R332.1[医药卫生—人体生理学] R337.5[医药卫生—基础医学]