异位宁对子宫内膜异位症大鼠血清白介素2及白介素10作用的实验研究  

The Effefct of Yiweining on the Contents of IL-2 and IL-10 in the Model Rat with Endometriosis

作　　者：曲凡[1] 马文光[1] 杨东霞[1] 马宝璋[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《时珍国医国药》2006年第11期2153-2154,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家教育部高等学校博士学科点专项科研基金资助项目(No.20050228001);黑龙江省自然科学基金资助项目(No.D2004-55);黑龙江省研究生创新科研资金项目

摘　　要：目的通过研究异位宁对子宫内膜异位症大鼠血清IL-2、IL-10的影响来阐述异位宁的作用机理。方法采用自体子宫组织块移植法建立子宫内膜异位症大鼠模型。应用ELISA的方法,检测大鼠异位子宫内膜IL-2,IL-10含量。结果异位宁高剂量组IL-2含量明显高于模型对照,有显著性差异(P<0.01);IL-10含量明显低于模型对照组,有显著性差异(P<0.01)。结论异位宁可以通过降低IL-10水平,而升高IL-2进而提高细胞免疫功能,从而达到治疗子宫内膜异位症的目的。Objective To clarify the effect of YWN in treating endometriosis through measuring the contents of IL-2 and IL-10, Methods Operational self-transplantation was applied in establishing animal models, Detection of IL-2 and IL-10 was conducted with ELISA. Results There existed significant difference in the contents of IL-2 and IL-10 between YWN group and control group. Conclusion YWN can functions well in curing EM through reducing IL-10 level and increasing IL-2 level.

关 键 词：异位宁 白介素2 白介素10 

分 类 号：R285.5[医药卫生—中药学]