多巴酚丁胺心电图与^（99m）Tc－MIBI心肌显像对冠心病诊断价值比较  

COMPARISON OF DOBUTAMINE ELECTROCARDIOGRAPHY WITH TECHNETIUM-99M-MIBI SPECT FOR DIAGNOSIS OF CORONARY ARTERY DISEASE

作　　者：陈步星[1] 徐成斌[1] 王伟民[1] 田雅文[1] 高伯山[1] 齐桂英[1] 

机构地区：[1]北京医科大学人民医院心内科

出　　处：《北京医科大学学报》1996年第5期355-357,共3页Journal of Peking University(Health Sciences)

摘　　要：目的：比较多巴酚丁胺心电图（Ｄｏｂｕ－ＥＣＧ）与￣（９９ｍ）Ｔｃ－ＭＩＢＩ心肌显像（Ｄｏｂｕ－ＥＣＴ）诊断冠心病的价值。方法：对６９例拟诊冠心病而无心肌梗塞患者在行冠状动脉造影时进行多巴酚丁胺心肌显像检查。结果：Ｄｏｂｕ－ＥＣＴ诊断冠心病的敏感性和准确度优于Ｄｏｂｕ－ＥＣＧ（９１．７％对４７．２％，Ｐ＜０．０１８，５．５％对６６．７％，Ｐ＜０．０５），特异性二者之间无差异。诊断冠状动脉单支、双支、三支病变的敏感性Ｄｏｂｕ－ＥＣＴ优于Ｄｏｂｕ－ＥＣＧ。诊断前降支、右冠状动脉的敏感性，Ｄｏｂｕ－ＥＣＴ高于Ｄｏｂｕ－ＥＣＧ。在研究中无一例出现严重副作用。结论：Ｄｏｂｕ－ＥＣＴ对识别冠心病存在与否及冠心病冠脉病变程度和范围均优于Ｄｏｂｕ－ＥＣＧ。Objective: To compare the value of dobutamine electrocardiography (Dobu-ECG)with that of ￣(99m)Tc-MIBI single photon emission computed tomography (Dobu-ECT)in detecting coronary artery dis-ease(CAD).Methods:Sixty-nine patients with suspected CAD without previous myocardial infarction were studied prospectively with Dobu-ECT at the time of coronary angiography,Results:The sensitivi-ty and accuracy of Dobu-ECT were better than those of Dobu-ECG(91.7%vs 47.2%,P<0. 01;85.8%vs,66.7%,P<0.05;respectively),and specificity between Dobu-ECT and Dobu-ECG was not sig-nificant. In diagnosing single, double, triple-vessel diseases,the sensitivity of Dobu-ECT was superior to that of Dobu-ECG In identifying the stenoses of left anterior descending and right coronary artery,the sensitivities of Dobu-FCT were higher than those of Dobu-ECG. No serious side effects were ob-served in the study. Conclusion:Dobu-ECT in identifying whether CAD or the extent and location of CAD was superior to Dobu-ECG.

关 键 词：多巴酚丁胺 诊断 冠心病 锝^99M 

分 类 号：R541.404[医药卫生—心血管疾病]