十三味中草药体外抗淋球菌的作用研究  

Study of Inhibitory Effects of Thirteen Kinds of Chinese Herbal Medicines on N.gonorrhoeae in Vitro

作　　者：陈枝岚[1] 谢守珍[1] 

机构地区：[1]广州军区武汉总医院妇产科,武汉430070

出　　处：《华南国防医学杂志》2006年第5期22-24,共3页Military Medical Journal of South China

摘　　要：目的探讨13味中草药对淋球菌的抑制作用。方法采用平板打孔法和平板稀释法,分别测定了13种中草药体外抗淋球菌的效果。结果显示黄连的最小抑菌浓度(MIC)值为6.25mg/ml,石榴皮、虎杖的MIC值为12.5mg/ml,黄柏、丁香、五倍子、诃子的MIC值为25mg/ml。结论对淋球菌有明显抑菌作用的单味药有黄连、石榴皮、虎杖,其次有黄柏、丁香、五倍子、诃子,并以黄连作用为最强。Objiective To explore the inhibitory effects of 13 kinds of Chinese herbal medicines on N. gonorrhoeae in vitro. Methods The thirteen kinds of Chinese herbal medicines mainly inclnded Eugenia caryophyllata Thunb, Coptis chinensis Franch, Polygonum cuspidatum, et Zucc, Rhus chinensis Mill, Agrimonia pilosa Lcdcb, Pulsatilla chincnsis（Bge. ）Rcgel and so on. The ethnal extrac was made from each of thirteen kinds of Chinese herbal medicines and diluted to different concentrations. Then their bacteriostasis were observed and minimum concentration （MIC） of inhibition of N. gonorrhoeae was determined. Results The MIC of Coptis chinensis Franch was 6.25mg/ml; The MIC of Pericarpium granati and Polygonum cuspidatum, et Zucc was 12.5mg/ ml; The MIC of Phellodendron chinese Schneid ,Eugenia caryophyllata Thunb and Rhus chinensis Mill was 25mg/ml. The MIC of Sophrra flavescens Ait was 100mg/ml. Conclusions Coptis chincnsis Franch,Pericarpium granati, Polygonum cuspidatum, et Zucc ,Phellodendron chinese Schneid, Eugenia caryophyllata Thunb and Rhus chinensis Mill have strong inhibitory effects on N. gonorrhoeae in vitro. The Coptis Chinensis Franch has the strongest effect on N. gonorrhoeae in 13 kids of Chinese herbal medicines.

关 键 词：中草药 淋球菌 抑菌浓度 

分 类 号：R282[医药卫生—中药学]