^(99m)Tc-MIBI心肌断层显像肺摄取的定量分析  

Quantification of ^(99m)Tc-MIBI lung uptake in myocardial SPECT studies

作　　者：屈婉莹[1] 鲁振萍[1] 周颖[1] 何青[1] 

机构地区：[1]北京医院核医学科,100730

出　　处：《中华核医学杂志》1996年第4期217-219,共3页Chinese Journal of Nuclear Medicine

摘　　要：为评价^(99m)Tc-甲氧基异丁基异腈(MIBI)心肌断层显像肺摄取定量分析对判断左心功能障碍的价值,42例对照者和65例冠心病患者1周内完成^(99m)Tc-MIBI 心肌 SPECT 显像和核素心室显像。自心肌 SPECT 采集图像的前位投影图计算运动和静息态肺心计数比值(LHR);利用核素心室显像测定左室射血分数(LVEF)。结果:对照组 LHR 运动较静息时低(P<0.01);冠心病组 LHR 运动和静息时均较对照组高;运动和静息 LHR 与 LVEF 呈高度负相关,r 分别为-0.6113和-0.623 4,P 均<0.001。结论:运动和静息态 LHR 与 LVEF 相关,LHR 可预测左室功能。PURPOSE To assess the significance of ^(99m)Tc-MIBI lung uptake during myocardial SPECT studies in the evalua- tion of left ventricular dysfunction.METHODS 42 control subjects and 65 patients with coronary artery disease (CAD) were in- vestigated with ^(99m)Tc-MIBI myocardial SPECT and radionuclide ventriculography (RNV) within 1 week.The lung-to-heart ratios (LHR) both at rest and exercise were calculated from the anterior projection of the SPECT image sets.The left ventricular ejec- tion fraction (LVEF) was determined using RNV.RESULTS In the control group,a significant decrease in LHR was observed during exercise (P<0.01).The CAD group showed significantly high LHR values both at rest and exercise.A negative correla- tion was observed between LHR values and LVEF at rest (r=-0.623 4,P<0.001) and exercise (r=-0.6113,P< 0.001).CONCLUSIONS LHR both at rest and exercise are significantly correlated with LVEF and may be useful in the evalua- tion of left ventricular function.

关 键 词：冠心病 CT 心脏功能试验 锝^99M 

分 类 号：R541.4[医药卫生—心血管疾病]