月桂氮卓酮的抑菌谱研究  

STUDY ON BACTERIOSTATIC SPECTRUM OF LAUROCAPRAM(AZON)

作　　者：刘体全[1] 王雅莉 齐林[3] 郝勇[1] 隋慧雪[1] 黄凯[1] 范丽娜[1] 王利青[1] 

机构地区：[1]白求恩军医学院,石家庄050081 [2]河北省围场县医院 [3]河北省卫生厅卫生监督局

出　　处：《中国消毒学杂志》2006年第6期536-538,共3页Chinese Journal of Disinfection

摘　　要：为研究月桂氮卓酮抑菌谱,采用液体培养基倍比稀释法对47株细菌和1株支原体抑菌作用进行了实验室观察.结果,含40 μg/ml氮酮对25株革兰阳性和革兰阴性细菌繁殖体都有强抑菌作用;对破伤风芽孢杆菌等5株厌氧菌也有有抑菌作用;对支原体有抑制作用.含20 μg/ml氮酮对20株革兰阳性和革兰阴性杆菌和球菌也有较强的抑菌作用.对大肠杆菌等22株革兰阴性杆菌无抑菌作用.结论, 20～40 μg/ml月桂氮卓酮对所试革兰阳性和革兰阴性细菌、部分厌氧菌和支原体具有抑菌作用,对大肠杆菌等22株革兰阴性杆菌无抑菌作用.In order to study bacteriostatic spectrum of laurocapram, liquid culture medium specific dilution method was used to carry out laboratory observation on inhibiting effect on 47 strains of bacteria and 1 strain of Mycoplasma. Results： 40 μg/ml laurocapram had strong inhibitory effect on 25 strains of gram - positive （ G^ ＋ ） and gram - negative （ G^- ） vege- tative forms of bacteria and also inhibitory effect on 5 strains of anaerobes such as Clostridium tetani and Mycoplasma. 20 μg/ml laurocapram had strong inhibitory effect on 20 strains of G^＋ and G^- bacilli such as Escherichia coli. Conlusion. 20 ～ 40 μg/ml laurocapram has inhibitory effect on some G^＋ and G^- bacteria, some anaerobes and Mycoplasma , but had no inhibitory effect on 22 strains of G^- bacilli such as Eshcerichia coli.

关 键 词：月桂氮卓酮 细菌 厌氧菌 支原体 抑菌谱 

分 类 号：R187.2[医药卫生—流行病学]