急诊重症监护病房患者下呼吸道感染铜绿假单胞菌的研究  

Pseudomonas aeruginosa Infection in EICU Patients with Lower Respiratory Infections

作　　者：王瑾[1] 闫亮[2] 王昆[1] 谷晓英[3] 

机构地区：[1]解放军总医院,北京100853 [2]解放军302医院,北京100039 [3]蚌埠医学院药学专业,安徽蚌埠230000

出　　处：《中华医院感染学杂志》2006年第11期1305-1306,共2页Chinese Journal of Nosocomiology

摘　　要：目的 探讨急诊重症监护病房（EICU）下呼吸道感染患者铜绿假单胞菌分布特征及其耐药性。方法 对2005年8月-2006年2月间，在医院EICU收治的25例下呼吸道感染患者的临床资料进行分析。结果 在EICU的25例下呼吸道感染患者中，共分离出病原菌81株，革兰阳性菌32．1％，革兰阴性菌43．2％，真菌24．7％；其中铜绿假单胞菌占13．6％；铜绿假单胞菌药敏结果表明头孢噻肟、庆大霉素、复方新诺明、米诺环素、左氧氟沙星、加替沙星等抗菌药物耐药。结论 铜绿假单胞菌感染与耐药是EICU中下呼吸道感染患者治疗中的重要问题，应引起重视。OBJECTIVE To investigate the distribution of Pseudomonas aeruginosa and its antibiotic resistance in emergency intensive care unit （EICU） patients with lower respiratory infections. METHODS The data of the pathogens isolated in sputum from the 25 patients with lower respiratory infections admitted to EICU from Aug 2005 to Feb 2006 were collected and analyzed. RESULTS Eighty-one bacteria strains were found in these 25 EICU cases. The Gram-negative bacteria were the main pathogens of infection （43.2%）, after them were Gram-positive bacteria （32.1%）, and fungi （24.7%）. The percentage of P. aeruginosa infection was 13.6% of all patients. The antibiotic resistance for P. aeruginosa was found to the antibiotics, such as cefotaxime, gentamicin, SMZ-TMP, minocycline, levofloxacin, and gatifloxacin. CONCLUSIONS The P. aeruginosa infection and its antibiotic resistance should be paid more attention in the treatment of the lower respiratory infection patients in EICU.

关 键 词：EICU 下呼吸道 铜绿假单胞菌 耐药性 

分 类 号：R515[医药卫生—内科学]