乳源性胰岛素对新生仔猪肠道生长和组织形态学的影响  

Effect of Dietary Insulin on the Development of Gastrointestinal Tract in Neonatal Pigs

作　　者：霍永久[1] 王恬[1] 许若军[2] 

机构地区：[1]南京农业大学动物科技学院,江苏南京210095 [2]香港大学动物学系

出　　处：《家畜生态学报》2006年第5期42-45,共4页Journal of Domestic Animal Ecology

基　　金：国家自然科学基金项目(30471253)

摘　　要：研究了乳源性胰岛素对新生仔猪小肠生长和组织形态学的影响。随机选择5头初生苏太仔猪,生后立即屠宰取样,作为新生对照组(N)。另外,从五窝初生仔猪中选10头仔猪,每窝选2头,分别分到饲喂牛乳组(M)和牛乳加入胰岛素组(M I)(添加量为2.5 mg/L)。M组和M I组仔猪出生后用牛乳人工喂养3天后屠宰取样。结果表明,M I和M组小肠长度分别极显著(P<0.01)和显著(P<0.05)高于N组。M I组的非粘膜重有高于M组的趋势(P=0.148)。M I组空肠后段和回肠前段绒毛高度分别极显著(P<0.01)和显著(P<0.05)高于M组。M I组各肠段绒毛高度/隐窝深度均高于N组(P<0.01或P<0.05),其中空肠前段和后段分别显著(P<0.05)和极显著(P<0.01)高于M组。结果提示:乳源性胰岛素能够刺激新生仔猪小肠生长并影响到小肠的组织形态。The experiment was conducted to examine the effect of dietary insulin on the development of gastrointestinal tract in neonatal pigs. Five piglets were anesthetized and sampled within 2 -4 hours after birth without suckling and used as newbom control （ group N）. Ten other piglets from 5 litters werc randomly divided into group M （n =5）, which were fed cow, and group MI （n =5）, which were fed cow milk plus insulin （2.5 mg/L）. The piglets of groups M and MI were artificially fed for 3 days and then anesthetized and sampled. Results showed that the small intestinal length in groups MI and M was higher （ P 〈 0. 01 and P 〈 0.05 , respectively） than in group N. The non-mucosal weight of small intestine in group MI had the tendency to be higher （P = 1. 148 ） than in group M. The villus height of small intestine in groups MI and N showed no significant difference （ P 〉 0. 05 ）. The villus heights of distal jejunum and primal ileum in group MI were higher （ P 〈 0.01 and P 〈 0. 05 , respectively） than that in group M. The villus height/crypt depth of the small intestine in group MI was higher （ P 〈 0.01 or P 〈 0. 05 ） than that in group N. The Villus height/crypt depth of primal and distal jejunum was higher （ P 〈 0.05 and P 〈 0.01 , respectively） than that in group M. Collectively, we conclude from the data that dietary affects the intestinal growth and morphology.

关 键 词：仔猪 小肠 胰岛素 生长发育 

分 类 号：S811.5[农业科学—畜牧学]