肉苁蓉中苯乙醇苷类化合物的分离提取及电喷雾质谱研究  

Extraction and ESI-MS^n Studies of Phenylethanoid Glycosides in Cistanche deserticola

作　　者：李丽[1] 刘春明[2] 刘志强[1] 吕磊[1] 刘淑莹[1] 

机构地区：[1]中国科学院长春应用化学研究所长春质谱中心,吉林长春130022 [2]长春师范学院化学系,吉林长春130032

出　　处：《质谱学报》2006年第4期232-236,共5页Journal of Chinese Mass Spectrometry Society

基　　金：国家自然科学基金(批准号:20173057);中国科学院知识创新工程重要方向项目(批准号:KGCX2-SW-213-06)资助项目

摘　　要：采用电喷雾多级串联质谱技术,对肉苁蓉药材粗提物中的苯乙醇苷类化合物的特征质谱行为进行了系统研究,根据一些特征的中性碎片丢失,提出了该类化合物的质谱裂解规律。通过得到的分子量和碎片信息并与标准化合物以及文献中的已知化合物比较,建立了这一类化合物快速鉴定的质谱新方法。The structures of phenylethanoid glycosides in plant extract of Cistanches deserticola were successfully analyzed and identified by electrospray ionization multi-stage mass spectrometry （ESI-MS^n） in negative mode, some interesting neutral losses were found, which helped us to confirm the structures of compounds without tedious separation and purification procedures, then the fragmentation mechanisms were explored. The identification of the phenylethanoid glycosides in plant extract of Cistanche deserticola was based on the comparison of molecular ions, and the fragment ions obtained by MS^n experiments with those of the authentic standards and the data was reported in the literatures.

关 键 词：肉苁蓉 苯乙醇苷类化合物 电喷雾多级串联质谱 

分 类 号：O657.63[理学—分析化学] R917[理学—化学]