成年男性血清生殖激素水平与精液量以及精子密度的关系  

Relationships between Serum Reproductive Hormones and Sperm Density as well as Semen Volume in Chinese Adults

作　　者：闫蓓[1] 高尔生[2] 崔元起[3] 武俊青[2] 周维谨[2] 袁伟[2] 

机构地区：[1]复旦大学公共卫生学院,上海200032 [2]上海市计划生育科学研究所,上海200032 [3]上海市人口和计划生育委员会,上海200003

出　　处：《生殖与避孕》2006年第11期679-683,共5页Reproduction and Contraception

基　　金：国家人口和计生委资助项目;项目编号为9902

摘　　要：目的:探索普通成年男性血清生殖激素水平与精液量以及精子密度的关系。方法:资料来源于对5个研究现场(河北省石家庄市、山西省太原市、贵州省贵阳市、浙江省杭州市及山东省青岛市)的普通成年男性的横断面调查。同时收集研究对象的血样和精液样本,分析黄体生成素(LH)、卵泡刺激素(FSH)、睾酮(T)以及雌二醇(E2)与精液量、精子密度之间的关系。结果:共招收研究对象978名,通过相关分析及方差分析表明,高水平T对象的精子密度较低;高水平E2对象精液量较少。Logistic回归分析发现,高水平T发生低精子密度的危险性大,低水平的LH发生低精子密度的危险性小。结论:普通成年男性血清中生殖激素水平与精液数量指标有关,但表现出的某些关联性用已知的下丘脑-垂体-睾丸轴调节机制尚无法完全解释。Objective： To investigate the relationships between serum reproductive hormones and sperm density and semen volume in ordinary adult men. Methods： This study was a cross-sectional epidemiological survey, combined with laboratory measures of hormonal profiles （FSH, LH, T, and E2） and semen. The data came from the ordinary volunteers in 5 selected cities of China （Shi Jiazhuang, Tai Yuan, Hang Zhou and Qing Dao）. Results： A total of 978 eligible subjects were recruited, the liner correlation analysis and variance analysis showed that sperm density was significantly lower in high T group compared with low groups, and semen volume in high E2 group was less than low groups. The logistic regression analysis showed that high T group had a higher risk for low semen density and low FSH had a lower risk. Conclusion： Semen measures in ordinary adult men were related to serum reproductive hormones, but well-known hypothalamic- pituitary-testicular axis could not fully explain their relationships.

关 键 词：生殖激素 精子密度 精液量 

分 类 号：R698[医药卫生—泌尿科学]