高原肺水肿超微结构变化  

ULTRASTRUCTURE OF HIGH ALTITUDE PULMONARY EDEMA

作　　者：牟信兵[1] 洪青元[1] 朱素琼[1] 罗登成 肖琦[1] 

机构地区：[1]西藏军区总医院高山病防治研究中心

出　　处：《高原医学杂志》1996年第3期25-26,共2页Journal of High Altitude Medicine

摘　　要：本文使用电镜对高原肺水肿患者及同海拔健康者各４名肺组织的超微结构改变进行观察，结果揭示肺水肿患者呼吸系统广泛水肿，肺泡上皮细胞明显肿胀、水肿，肺泡Ⅱ型上皮细胞损害较重，肺毛细血管细胞连接间隙增宽，气血屏障内外侧结构局部缺损，这些形态学改变是高原肺水肿作为一种高蛋白、高渗出性肺水肿的病理基础。o explore the mechanism of high altitude pulmonary edema (HAPE),we observed the ul-trastructural changes in the lungs in 4 patients with HAPE,4 high altitude healthy subjects wereused as controls.It was found nnder electron microscopy that the enclothelial cells were significantly swollenand interpreted as cytoplasmic edema;Type一Ⅱ epithelial cell edema and rupture were present;In-tercellular junctions were widened and broken; Gas一blood barriers were thinned.The authorsconsidered that A high-high-protein edoma of HAPE was based on the ultrastruc-tural changes in this study.

关 键 词：高原病 肺水肿 高原肺水肿 超微结构 

分 类 号：R594.302[医药卫生—内科学] R541.630.2[医药卫生—临床医学]