多相手性催化剂的制备及其对不对称加氢反应的催化作用  

Preparation of heterogeneous chiral catalysts and their application to asymmetric hydrogenation

作　　者：吴跃[1] 薛屏[1] 

机构地区：[1]宁夏大学能源化工重点实验室,宁夏银川750021

出　　处：《化工进展》2006年第11期1301-1308,共8页Chemical Industry and Engineering Progress

基　　金：国家重大基础研究前期研究专项项目(2004CCA05900)

摘　　要：综述了不对称加氢反应中多相手性催化剂的研究进展,包括将均相手性催化剂固定到有机聚合物、磁性的Fe3O4纳米颗粒、功能化修饰的分子筛等载体上;直接利用有机金属配合物中的阳离子和分子筛骨架中的阴离子相互作用实现多相化;采用金鸡纳生物碱等手性小分子为修饰剂和天然高分子为手性源制备多相催化剂。同时对不同途径制备的多相手性催化剂的结构特性、催化性能和立体选择性进行了评价。The preparation of heterogeneous chiral catalysts for asymmetric hydrogenation by the immobilization of homogeneous catalysts on polymer, Fe3O4 nanoparticles or functionalized molecular sieves was reviewed. The interaction between the negatively charged molecular sieve framework and the cation of the organometallic complex; modification of chiral micromolecular （such as Cinchona alkaloid） and application of natural chiral biopoly mers were discussed. Their activities, enantioselectivities, and characteristics in asymmetric hydrogenation were also introduced.

关 键 词：手性催化剂 多相催化剂 不对称加氢 对映选择性 

分 类 号：O643.322[理学—物理化学]