部分脾栓塞治疗难治性原发性血小板减少性紫癜的疗效观察  

Clinical Research of the Partial Splenic Embolization in the Treatment of the Refractory Idiopathic Thrombocytopenic Purpura

作　　者：赵恒[1] 邬国和[1] 刘定胜[1] 李传庭 李东宁[1] 颜丽华[1] 李萍[1] 

机构地区：[1]南昌大学第三附属医院血液科,江西南昌330008

出　　处：《医学临床研究》2006年第11期1800-1802,共3页Journal of Clinical Research

摘　　要：目的探讨部分脾栓塞在治疗难治性原发性血小板减少性紫癜(ITP)的临床疗效和应用。方法对9例难治性ITP患者进行部分脾栓塞治疗,其中3例短期有效而又复发者进行脾切除治疗,观察和随访其临床疗效。结果9例病人中有8例(包括脾切除术3例)完全缓解,缓解率达88.9%,1例无效。其中随访2年以上4例,1年以上2例,半年以上2例,均无复发。结论部分脾栓塞保留了脾脏的免疫功能,并发症少,临床疗效满意,是治疗难治性ITP安全可靠的方法,亦可作为脾切除治疗难治性ITP的一个手术指标。[Objective]To investigate the clinical therapeutic effect of the partial splenic embolization in the treatment of refractory idiopathic thrombocytopenic purpura（ITP）. [Methods]Nine patients with refractory ITP were treated with the partial splenic embolization and followed-up, the clinical therapeutic effects were observed,3 recidivists of short-term effect were given splenectomy. [Results]Eight patients （including 3 recidivists） of them were in complete remission （88.9%）, 1 patient was ineffective. Four patients were followed-up above 2 years, 2 above 1 year and 2 above half a year. No recurrence occurred in these 8 patients. [Conclusion] The partial splenic embolization retains immune function of spleen and has less complications and its clinical therapeutic effect is satisfactory. So it is a safe and reliable method and can replace splenectomy to treat refractory ITP.

关 键 词：紫癜 血小板减少性/治疗 栓塞 治疗性/疗法 

分 类 号：R554.1[医药卫生—血液循环系统疾病]