中药质量控制的研究策略和色谱技术  

Strategy of Quality Control for Traditional Chinese Medicines and Chromatographic Technology

作　　者：李发美[1] 熊志立[1] 鹿秀梅[1] 秦峰[1] 李小芩[1] 

机构地区：[1]沈阳药科大学药学院,辽宁沈阳110016

出　　处：《色谱》2006年第6期537-544,共8页Chinese Journal of Chromatography

基　　金：国家自然科学基金资助项目(No.30472168);国家科技攻关计划项目子课题(No.2001BA701A56)

摘　　要：综述了色谱技术作为现代高效分离分析技术在中药药效物质基础研究和中药质量控制中的重要作用。提出中药药效物质组学研究策略,以实现中药药效物质基础与作用机理研究的一体化,进而从深层次揭示和全面控制中药的内在质量。论述结果表明,现代色谱及其联用技术是中药质量研究的重要技术平台之一。The application of chromatography, a modern technology for highly efficient separation and analysis in the research of therapeutic basis matter and quality control of traditional chinese medicine （TCM）, is summarized. A new strategy with metabonomics is put forward to achieve integral study on therapeutic basis matter and action mechanism of TCM, and to reveal and control the comprehensive quality of TCM. Modern chromatography and hyphenated techniques are one of the important technique platforms in quality control of TCM.

关 键 词：中药 质量控制 色谱技术 中药药效物质组学 综述 

分 类 号：O658[理学—分析化学]