孕妇尿碘与补碘关系探讨  

The relationship of urinary iodine level and iodine supplement of pregnant women

作　　者：张丽江[1] 赵耘[1] 王山米[1] 

机构地区：[1]北京大学人民医院产科

出　　处：《Journal of US-China Medical Science》2005年第2期28-32,共5页美中医学（英文版）

摘　　要：目的 观察不同孕周、不同碘营养状况下孕妇尿碘，分析孕妇碘营养状况及药物治疗的必要性。方法 收集1997年7月-2003年3月期间，在我院就诊及分娩的孕产妇的尿标本18，528例次，检测她们的尿碘值。分组：A组为未补充“金典”组，B组为补充“金典”组；孕早期为1组，孕中期为2组，孕晚期为3组。结果（1）本实验资料尿碘中位数为231μg/L，孕产妇尿碘值〈50μg／L、〈100μg／L、〈200μg／L的发生率分别为2．4％、13．9％及43．4％；（2）孕早、中、晚期未补充“金典”组尿碘值分别为162μg／L、193μg／L、260μg／L。均低于同期补充“金典”组（377μg／L、286μg／L、382μg／L），其差异有显着性（P=0．000）；（3）随着孕周的增加，未补充“金典”组尿碘值依次升高，其差异有显着性（P=0．000）。结论 （1）在我院就诊分娩的孕妇存在一定程度的碘营养缺乏状况；（2）尿碘值代表了孕妇的碘营养状况，应检测尿碘以指导补碘。We have investigated the urinary iodine level of pregnant women during different periods of pregnancy and different iodine nutrition condition and analysed iodine nutrition condition of pregnant women and necessity of medicine therapy. Having selected 18, 528 urinary samples of pregnant women from 1997.7 to 2003.3 in our hospital and measured their urinary iodine, we separated them into different groups according to whether supplying iodine or not： A group was non-iodine supplying group, B group was iodine-supplying group. The first trimester was 1st group, the second trimester was 2nd group and the third trimester was 3rd group. After measurement, we found that： （1） The median urinary iodine of all the cases was 231μg/L. The incidence rates of urinary iodine level 〈50μg/L, 〈100μg/L and 〈200lμg/L were 2.4%, 13.9% and 43.4%, respectively. （2）In the first, second and third trimester, the urinary iodine levels of non-iodine-supplying group were 1621μg/L, 1931μg/L and 260μg/L, respectively, lower than those of iodine-supplying group in the same gestational period （377μg/L, 286μg/L, 382μg/L） （P=0.000）. （3） The urinary iodine level of non-iodine supplying group was significantly increased along with the increase of pregnant weeks（P=0.000）. Than we can draw the conclusion that： （1）Pregnant women in our hospital have iodine-deficient condition for a certain extent. （2） The urinary iodine level can reflect iodine nutrition condition of the pregnant women. We should measure the urinary iodine to guide iodine supplement.

关 键 词：孕妇 新生儿 碘营养 尿碘 

分 类 号：R591.101[医药卫生—内科学]