乌贼墨对红细胞免疫粘附肿瘤细胞能力的影响  

EFFECTS OF SEPIA ON ERYTHROCYTE'S ADHESION TO TUMOR CELLS

作　　者：刘成玉[1] 滕青[2] 周绪样 谭润鸾[1] 

机构地区：[1]青岛医学院诊断学教研室,青岛266021 [2]青岛市浮山医院

出　　处：《中国海洋药物》1996年第3期14-16,共3页Chinese Journal of Marine Drugs

摘　　要：采用红细胞C_(3b)受体花环试验和肿瘤红细胞花环试验,检测了乌贼墨对正常人和肿瘤病人红细胞C(3b)受体活性及红细胞免疫粘附肿瘤细胞能力的影响。结果显示,乌贼墨对正常人和肿瘤病人红细胞C_(3b)受体具有明显的激活作用,乌贼墨浓度为10％时激活作用最强;乌贼墨能明显增强正常人和肿瘤人红细胞免疫粘附肿瘤细胞的能力,乌贼墨浓度为10％时,其增强作用最明显。提示乌贼墨的抗肿瘤作用与其激活红细胞的免疫粘附功能有关。By means of the erythrocyte C3b receptor rosett test and the tumor erythrocyte rosette test, we measured the effects of Sepia on the activity of the erythrocyte C3b receptor and the erythrocyte's immune adhesion to tumor cells in normal persons and in malignant tumor patients. The results showed that Sepia has a markedly active effect on the erythrocyte C3b receptor in normal persons and patients with malignant tumor, and this effect was highest when the concentration of Sepia was 10%. Sepia could markedly enhance the erythrocyte's immune adhesion to tumor cells in normal subjects and in patients with malignant tumor, which was more obvious when the concentration of Sepia was 10%. These results indicate that the anti-tumor action of Sepia is related to activating the erythrocyte immune adhesion function.

关 键 词：乌贼墨 红细胞 免疫粘附 肿瘤细胞 

分 类 号：R285.6[医药卫生—中药学] R282.740.5[医药卫生—中医学]