艾滋病合并马尔尼菲青霉菌感染二例的病理特点  

Two AIDS patients associated with penicilliosis marniffei

作　　者：马沛卿[1] 郎振为[1] 沈冰[1] 石晓虹[1] 刀文彬[1] 刘彦春[2] 李若瑜[2] 伦文辉[2] 

机构地区：[1]北京地坛医院病理科,100011 [2]北京地坛医院皮肤科,100011

出　　处：《中华传染病杂志》2006年第5期338-341,共4页Chinese Journal of Infectious Diseases

摘　　要：目的了解艾滋病合并马尔尼菲青霉菌感染的临床表现及组织病理学特点,探讨马尔尼菲青霉菌病的诊断及鉴别诊断。方法对2例活检标本进行常规苏木精-伊红染色及过碘酸-希夫染色、Gomori六胺银特殊染色,观察马尔尼菲青霉菌在组织中的形态特点,并结合文献进行讨论。结果在组织内可见酵母状真菌,过碘酸-希夫染色、Gomori六胺银真菌染色阳性,可见呈腊肠样结构并具有横隔。结论组织病理学检查,马尔尼非青霉菌具有较典型的形态结构。Objective The study was to investigate the clinical and histopathological features of pencillium marneffei infection in patients with AIDS. Methods Two cases of penicillium marneffei infections of lymph node and intestinal mucosa were investigated morphologically by hematoxylin eosin （HE）, periodic acid Schiff（PAS） and Gomori＇s methenamine silver（GMS） staining and the related literatures were reviewed. Results Small yeast-form fungi were detected in tissue sections by HE staining and sausage-like structures and septum formations were demonstrated clearly by PAS and GMS staining. Conclusions Penicillium marneffei infection can be diagnosed histopathologically if its characteristic structures are observed in tissue sections with positive PAS and GMS staining.

关 键 词：获得性免疫缺陷综合征 青霉属 真菌菌病 

分 类 号：R512.91[医药卫生—内科学] R519[医药卫生—临床医学]