RP-HPLC法测定妇康胶囊中人参皂苷Rg_1的含量  

Determination of Qinsenoside Rg_1 in Fukang Capsules by HPLC

作　　者：于风平 代秀梅 姜华 崔丽华 徐丽华 

机构地区：[1]淄博市药品检验所,淄博255000

出　　处：《齐鲁药事》2006年第11期659-660,共2页qilu pharmaceutical affairs

摘　　要：目的建立妇康胶囊中人参皂苷Rg1的含量测定方法，为该药品提供质量控制标准。方法采用反相HPLC法，以十八烷基硅烷键合硅胶为填充剂，乙腈-0．05%磷酸（20：80）为流动相，检测波长为203nm。结果线性范围为0．4008～2.004μg，相关系数为0．9999，加样回收率为99．15％。结论本方法可快速简便的控制妇康胶囊的质量。OBJECTIVE To establish a method for determination of ginsenoside Rg1 in Fukang Capsules by RPHPLC. METHODS RP-HPLC method was used. The mobile phase was acetonitrile 0.05% phosphoric acid solution（20 ： 80） . Detection wavelength was 203nm. RESULTS The standard curve was linear in the concentration range of 0. 4008-2. 004μg, r =0. 9999,the average recovery was 99.15%. CONCLUSION This method had good repeatability and flexibility. It can be used for quality control of Qinsenoside Rg1 in Fukang Capsules.

关 键 词：妇康胶囊含量测定 反相高效液相色谱法 人参皂苷RG 

分 类 号：R927.2[医药卫生—药学]