物理发泡法制备羟基磷灰石/胶原蛋白多孔支架材料  

Preparation of Hydroxyaptite/Collagen Protein Porous Scaffolds by Physical Foaming Method

作　　者：韩长菊[1] 叶金凤[1] 陈庆华[1] 张峰[1] 景森[1] 

机构地区：[1]昆明理工大学材料与冶金工程学院,云南昆明650093

出　　处：《佛山陶瓷》2006年第11期8-10,共3页Foshan Ceramics

摘　　要：本文以氢氧化钙悬浮液和磷酸为主要实验原料,在室温25℃,pH值为11的条件下,用共滴定的方法合成羟基磷灰石。把羟基磷灰石粉与一定量的胶原蛋白溶液混合,经过物理发泡、冷冻、微波干燥的过程,得到羟基磷灰石/胶原蛋白多孔支架材料。运用XRD、SEM分析仪器和阿基米德原理及杠杆原理,对样品进行了检测。结果表明用物理发泡法制得的多孔支架材料的总气孔率为79%～89%,抗压强度为0.3～1.1MPa。Hydroxyapatite was synthesized from Ca（OH）2 suspension and phosphoric acid,by simultaneous titration, at room temperature 25℃ ,pH=11. Hydroxyapatite/collagen protein porous scaffolds were prepared with hydroxyapatite powders mixed with collagen protein,via physical foaming, freezing and micro-wave drying, Pattern was characterized by XRD,SEM,the Archimedes＇method and the lever principle. The results showed that the porosity of the specimen was 79%-89% and the strength intensity was 0. 3-1. 1MPa.

关 键 词：羟基磷灰石 胶原蛋白 支架材料 物理发泡 

分 类 号：R318.08[医药卫生—生物医学工程]