染料中间体N-氰乙基-N-乙酰氧乙基苯胺的合成  

Synthesis of the Dyestuff Intermediate N-cyanoethyl-N-acetoxyethylaniline

作　　者：郑静[1] 魏先红[1] 梁伟[1] 

机构地区：[1]湖北师范学院化学与环境工程系,湖北黄石435002

出　　处：《甘肃科学学报》2006年第4期40-42,共3页Journal of Gansu Sciences

基　　金：湖北省教育厅科研基金项目(J200522002)

摘　　要：以N-羟乙基-N-氰乙基苯胺为原料,用冰醋酸做酰化剂,合成得到了染料中间体N-氰乙基-N-乙酰氧乙基苯胺.同时讨论了原料的摩尔比、反应温度、反应时间等对反应收率的影响.得到的最佳条件为:N-羟乙基-N-氰乙基苯胺与冰醋酸的摩尔比为1∶3,反应温度为140℃,常压反应精馏8 h,反应过程中将生成的水不断蒸出,得到产品N-氰乙基-N-乙酰氧乙基苯胺,纯度≥96%,收率达到89.8%.N.cyanoethyl-N-acetoxyethylaniline was synthesized from N-ethoxyl-N-cyanoethylaniline by using acetic acid as an acetylating agent. The influences of various factors on the reaction were studied and the optimum conditions were obtained. The molar ratio of N-ethoxyl-N-cyanoethylaniline and acetic acid was 1 - 3, the reaction temperature was 140℃, the reaction time was 8 hours and the water was evaporated by reactive rectification. The purity of N-cyanoethyl-N-acetoxyethylaniline can reach over 96%, and the yield can reach 89. 8%.

关 键 词：N-氰乙基-N-乙酰氧乙基苯胺 合成 酰化 冰醋酸 

分 类 号：O623.732[理学—有机化学]