膜分离与大孔树脂吸附技术在赤芍总苷提取与分离中的应用  

Effect of Versulin on Recovery of Function of Ischemic Retina of Rats

作　　者：陈寅生[1] 姚仲青[2] 

机构地区：[1]南京市中医院,江苏南京210001 [2]南京中医药大学药学院,江苏南京210046

出　　处：《南京中医药大学学报》2006年第6期406-406,408,共2页Journal of Nanjing University of Traditional Chinese Medicine

摘　　要：目的提取分离赤芍药材中的赤芍总苷。方法使用膜分离及大孔树脂吸附方法,提取、分离、纯化赤芍总苷。结果提取得到的赤芍总苷,其总苷含量以芍药苷计达85%以上;其中芍药苷含量可达75%。结论采用膜分离及大孔树脂吸附技术,提取分离、纯化赤芍总苷,方法可行。OBJECTIVE To observe the effect of versulin on the recovery of the function of ischemic retina of rats. METHOD Thirty rat retina ischemia models were made by artery ligation, divided into a treatment group of 20 rats treated with injected versulin and a control group of 10 rats treated with injected DMSO. Visual electric physiograph was used to examine the recovery of the function of retina. RESULT The retina function recovery in the treatment group was markedly more satisfactory than the control group （ P 〈 0.05）. CONCLUSION Versulin can promote the recovery of the function of ischemic retina of rats.

关 键 词：膜分离技术 大孔树脂吸附技术 赤芍总苷 提取分离 

分 类 号：R284.2[医药卫生—中药学]