腹膜透析并发腹膜炎的实验研究  

THE STUDY OF PERITONEAL DIALYSIS RELATED WITH PERITONITIS

作　　者：刘伏友 肖平 李军 

出　　处：《湖南医科大学学报》1996年第5期381-384,共4页Bulletin of Hunan Medical University

摘　　要：采用ｚｙｍｏｓａｎ和大肠杆菌注入新西兰兔腹腔，观察腹膜对白细胞、蛋白质、肌酐、葡萄糖的转运和水的超滤。结果显示，Ｚｙｍｏｓａｎ和大肠杆菌组透析液内白细胞数和蛋白质浓度增加，而小分子溶质肌酐、葡萄糖与对照组比较无差异；水超滤量在４．２５％葡萄糖透析液＋Ｚｙｍｏｓａｎ组高于对照组，而在０．９％ＮａＣｌ＋Ｚｙｍｏｓａｎ组，２．５％葡萄糖透析液＋Ｚｙｍｏｓａｎ组及２．５％葡萄糖透析液＋Ｅ－ｃｏｌｉ组与对照组比较均无差异。提示腹膜炎时大分子和小分子溶质的转运途径不同；不同渗透压的腹透液对水的转运机制可能不同。he dialysate with either Zymosan or E-Coli was instilled into the rabbit’s peritoneal cavitydwelling for 8 hrs to o6serve the transport of WBC,protein,creatinine,glucose and ultrafiltra-tion.The results demonstrated that WBC and protein in dialysate were increased.But there wasno difference of creatinine and glucose between the experimental group and the control.The ul-trafiltraion volume(UFV) was increased when 4.25%dialysis fluid plus Zymsan was dwelled,but there was no difference when 0.9%NaCl plus Zymosan or 2.5%dialysate plus either Zy-mosan or E-Coli was dwelled.The results suggested that the mechanisms mediating WBC migra-tion and protein loss may be depart form those mediating small solute clearance and ultrafiltra-tion.

关 键 词：腹膜透析 ZYMOSAN 大肠杆菌 腹膜炎 并发症 

分 类 号：R459.5[医药卫生—治疗学] R572.2[医药卫生—临床医学]