阿尔茨海默病病人认知训练与照顾者支持平行干预的效果评价研究  

A study on effect assessment on parallel intervention of cognitive training and supports of caretakers for Alzheimer disease patients

作　　者：杨莘[1] 张亚荣[2] 王玲[1] 王艳玲[2] 张燕莉[1] 李月梅[1] 董建[1] 杨培杰[1] 

机构地区：[1]首都医科大学宣武医院 [2]首都医科大学护理学院

出　　处：《护理研究（上旬版）》2006年第12期3118-3122,共5页Chinese Nursing Researsh

基　　金：北京市重点科技实验室北京脑老化研究实验室项目资助课题(批准号951890600)。

摘　　要：[目的]评价阿尔茨海默病(AD)病人认知训练与家庭照顾者支持相结合平行干预的效果。[方法]将26例居家AD病人及照顾者分为干预组与对照组。干预组病人及照顾者在益智训练室同步接受病人认知训练及照顾者支持的干预方案;照顾者指导AD病人在家每天固定时间训练及活动;开设专门电话热线,解答干预组AD病人及照顾者的相关问题;每周固定时间研究人员主动了解照顾者及病人在家训练情况。时间持续1年。对照组不进行干预。两组分别于3个月、6个月、12个月进行AD病人的简易智力状态检查量表(MMSE)、日常生活能力量表(ADL)、激越行为量表(CMAI)、功能活动调查表(FAQ)等功能状态和照顾者的Zung抑郁自评量表(SDS)、Zung焦虑自评量表(SAS)、家庭关怀度指数问卷(APGAR)及照顾者负担等评定指标随访评价。[结果]除CMAI得分,两组病人除6个月、12个月比较有统计学意义外,3个月、6个月、12个月,病人及照顾者的其余评定指标的差异均无统计学意义(P>0.05)。[结论]AD病人认知训练与家庭照顾者支持相结合的平行干预方案,尚缺乏延缓AD病情进展及减轻照顾者负担的正向结果;有必要进行多中心大样本的深入研究加以证实。Objective： To assess the effect of parallel intervention of cognitive training and supports of caregivers for Alzheimer disease （AD） patients. Methods： A total of 26 cases of patients with AD living at home and their caregivers were divided into intervention and control group. Patients and caregivers in intervention group accepted the interventional program of cognitive training and supports of caregiver for the patients in intelligence training room at the same time. Caregivers guided AD patients training and exercising at home in the fixation time. And special phone hotline was set up for answering the related questions of AD patients and caregivers asked in the intervention group. Every week in fixation time, researchers went to pay a home visit and to know about the training situation of patients and caregivers. This study had lasted for 1 year. However, patients of control group had not got any intervention at all. Indexes including MMSE,, revised ADL, CMAI, FAQ of patients and SDS, SAS, APGAR for caregivers and caregivers＇ burden were evaluated respectively follow up at 3 months, 6 months, 12 months of the two groups cases. Results： There was no statistic significance in the differences in terms of above mentioned indexes in patients and caregivers at 3 months, 6 months, and 12 months between the two groups cases （ all P 〉 0.05 ）. Except that in terms of CMAI scoring, there were statistical significant differences between the two groups cases at 6 months and 12 months respectivcly. Conclusion： The parallel intervention program for cognitive training of AD patients and sup- ports of familial caregivers is sill lack of positive results that can delay the aggravation of AD cases and reduce caregiver＇s burden. Therefore, multi - centered and large sample studies are necessary to be carried out to make sure the effectiveness of the program.

关 键 词：阿尔茨海默病 认知训练 照顾者负担 

分 类 号：R473.74[医药卫生—护理学]