830例狂犬疫苗接种后抗体检测结果分析  

Results of detection of antibody to rabies virus in 830 vaccinated subjects bitten by dogs.

作　　者：李怀昕[1] 汪武新[1] 谢远辉[1] 杨卫红[1] 彭晋先[1] 孙蔓[1] 耿艺介[1] 高世同[1] 黄达娜[1] 张仁利[1] 

机构地区：[1]深圳市疾病预防控制中心,广东深圳518020

出　　处：《中国热带医学》2006年第12期2153-2154,2156,共3页China Tropical Medicine

摘　　要：目的回顾分析2004年4月-2005年5月830例注射狂犬疫苗后抗体检测结果。方法用间接酶联免疫吸附法测血清抗体，自动酶标仪定性。被检对象分为12岁以下组、13～30岁、31-60岁组和61岁以上组。结果全部被检对象阳性率75．9％，国产疫苗阳性率高于进口疫苗，不同年龄组间差异无显著性。进口疫苗注射后检测弱阳性者一周内加强注射2针59％转阳，国产疫苗100％转阳。结论疗程内换用不同品牌疫苗对抗体的产生影响不大．国产疫苗效果好于进口疫苗。Objective To analyze the immune results of rabies vaccine in 830 vaccinated cases bitten by dogs. Methods IgG antibody against rabies virus was detected by using ELISA. The subjects were divided into three groups, namely Group Ⅰ consisted subjects under the age of 12 years, Group Ⅱ consisted of subjects in the age group between 12 and 30 years, Group Ⅲ consisted of subjects in the age group of between 31 and 60 years and Group Ⅳ consisted of those above the age of 61 years, Results The total positive rate was 75.9%. The domestic vaccine was superior to imported ones. No significant differences of immune effect were observed in different age groups. Conclusion Both domestic vaccine and imported vaccine can be used without affecting the immune results. The domestic vaccine is better than the imported one.

关 键 词：狂犬疫苗 抗体 阳性率 

分 类 号：R373.9[医药卫生—病原生物学]