深圳市从业人员中志贺菌型分布及药敏结果分析  

Analysis of distribution of serotype and drug resistance of Shigella in Shenzhen.

作　　者：邱亚群[1] 张倩[1] 黄新风[1] 孙卫[1] 冼慧霞[1] 

机构地区：[1]深圳市疾病预防控制中心,广东深圳518020

出　　处：《中国热带医学》2006年第12期2233-2233,共1页China Tropical Medicine

摘　　要：目的了掌握深圳市食品、公共场所从业人员志贺菌血清型分布和耐药情况。方法按国标肠道致病菌中志贺菌的检验方法和国家卫生行业标准WS/T 125-1999纸片法抗菌药物敏感试验标准方法进行。结果33株志贺菌分型,B群32株占总数的96.97%,C群1株占3.03%。在B群中,2型12株占36.36%,4型10株占30.30%,1型4株占12.12%,X变种5株占15.15%,Y变种1株。33株菌对庆大霉素、左旋氧氟沙星、氧氟沙星、诺氟沙星、环丙沙星、头孢噻腭、头孢唑啉、头孢美唑、痢特灵为100%敏感,对麦迪霉素100%耐药。结论深圳市食品、公共场所从业人员中志贺菌型分布有所改变;治疗菌痢应首选药物为痢特灵,环丙沙星,氧氟沙星等。Objective To understand the distribution and drug resistance of Shigella in food service workers in Shenzhen. Methods Based on the procedure identification of enterobacteria WS/T 125 - 1999 and disk diffusion method, the bacteria were isolated, identified and susceptibility test were carried out. Results 33 strains of Shigella were isolated and serotyped including 32 strains of Shigella B, occupied 96.97 % and 1 strain of Shigella C, occupied 3.03 %. Serotype A and D were not isolated. Among Shigella B, 12 were Shigella flexnerl 2 （accounted for 36.36% ）, 10 were Shigella flexneri 4 （30.30%）, 4 were Shigella flexneri 1 （12.12%）. 5 were Shigella flexneri X （15.15%） , 1 was Shigella flexneri Y （3.03%）. Drug susceptibility test revealed that Shigella was all sensitive to gentamyein, levofloxacin, ofloxacin, norfloxaein, ciprofloxacin, cefamczin cefmetazole, furazolidone and resistant to midecamycin. Conclusion Shigella isolated from food service workers has changed a little. Forazolidone, ciprofloxacin and ofloxacin are the drug of choice in clinical treatment of dysentery.

关 键 词：志贺菌 血清型分布 药敏试验 敏感 耐药 

分 类 号：R378.25[医药卫生—病原生物学]