QT离散度与冠状动脉病变程度关系的探讨  

Study on the relationship between QT dispersion and the severity of coronary artery disease

作　　者：廖树森 

机构地区：广西北海市人民医院心内科,北海536000

出　　处：《微创医学》2006年第3X期163-164,共2页Journal of Minimally Invasive Medicine

摘　　要：目的 探讨冠心病患者冠状动脉狭窄程度及范围与QT离散度（QTd）及校正QT离散度（QTcd）变化的关系及其临床意义。方法 将已行冠状动脉造影（CAG）的64例患者，按冠脉狭窄程度分为中度狭窄组（造影示病变狭窄〉50％-70％）18例、重度狭窄组（病变狭窄〉70％）20例；按冠脉血管狭窄支数分为单支病变组16例、2支以上病变组22例。将造影示狭窄〈50％，临床已排除冠心病的26例作为对照组。结果重度狭窄对QTd及QTcd影响明显（P〈0．005），而中度狭窄对QTd及QTcd则无明显影响（P〉0．05）；2支以上血管病变对QTd及QTed影响明显（P〈0．05），单支血管病变对QTd及QTcd则无明显影响（P〉0．05）。结论 冠心病患者QTd及QTcd与冠脉病变严重程度及血管病变范围有关，心肌缺血及损伤程度越重，其QTd及QTcd延长越明显，是评价冠心病患者心肌缺血及损伤的一个有意义指标。Objective To explore the relationship between the severity and stenosis of coronary artery stenosis and QT dispersion（QTd） and corrected QT dispersion（ QTcd）, and explore its clinical significance in patients with coronary heart disease. Methods Sixty-four patients underwent conorary angiography（CAG）. Eighteen patients who were proved to be coronary artery disease（CAD） with coronary artery stenosis ranging from 50% to 70% were enrolled in the moderate stenosis group. Twenty patients whose stenosis 〉 70% were enrolled in the severe stenosis group. Sixteen patients who were proved to be CAD with ene-vessel stenosis were enrolled in the one-vessel stenosis group. Twenty-two patients were enrolled in the over two-vessel group. Twenty-six patients who were proved not to be CAD with stenosis 〈 50% by conorary angiography were enrolled in the control group. Results The effectiveness on QTd and QTcd was significant in the severe stenosis group （ P 〈 0.005 ）, but not significant in the moderate stenosis group （ P 〉 0.05 ）. The effectiveness on QTd and QTcd was significant in the over two-vessel group （ P 〈 0.05 ）, but not significant in the one-vessel stenosis group （P 〉 0.05）. Conclusion The severity and stenosis of coronary artery had a relation with QTd and QTcd. More severe the myocardium ischemia and injury were , more obvious the QTd and QTcd extension will be,which maybe a significant index for evaluating the severity of myocardium isehemia and injury in patients with coronary heart disease.

关 键 词：冠心病 冠脉造影术 QT离散度 校正QT离散度 

分 类 号：R541.4[医药卫生—心血管疾病]